N-(3,4-Dimethylphenyl)-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide CAS 339027-82-6
| CAS No. | 339027-82-6 |
| Molecular Formula | C22H19F3N2O2 |
| Molecular Weight | 400.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(3,4-Dimethylphenyl)-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide.
N-(3,4-Dimethylphenyl)-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (CAS 339027-82-6), molecular formula C22H19F3N2O2 and molecular weight 400.39 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(3,4-Dimethylphenyl)-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (C22H19F3N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(3,4-Dimethylphenyl)-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H19F3N2O2 |
| Molecular Weight | 400.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- N-(2,4-Dimethylphenyl)-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (CAS 339027-91-7)
- N-(3,4-dimethylphenyl)-2-oxo-1-(4-(trifluoromethyl)benzyl)-1,2-dihydropyridine-3-carboxamide (CAS 400088-58-6)
- 1-(6-((2,5-Dimethylphenyl)thio)pyrimidin-4-yl)-N-(2-methoxyethyl)piperidine-4-carboxamide (CAS 1251549-69-5)
- (4-(2,4-Dimethylphenyl)piperazin-1-yl)(4-(2-methylbenzoyl)-1H-pyrrol-2-yl)methanone (CAS 478249-48-8)
- N-(2,5-Dimethylphenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 577763-65-6)
- N-(2,6-Dimethylphenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 482660-87-7)
- N-(3,4-Dimethylphenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 618427-81-9)
- N-(3,5-Dimethylphenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 585552-00-7)
Recommended Standards
- tert-Butyl 3-oxo-4-(2-oxo-2-(4-(trifluoromethyl)phenyl)ethyl)-1,4-diazepane-1-carboxylate (CAS 1998216-12-8)
- CAS 2591180-39-9 (CAS 2591180-39-9)
- Ethyl (2-(3-(4-ethoxyphenyl)-7-oxo-3,7-dihydro-6H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl)acetyl)glycinate (CAS 912617-98-2)
- Cinacalcet Impurity 75 (CAS CATO-C4X-105975)
- Sorbic Acid (CAS 110-44-1)
- 1-(1,8-Dioxa-4,11-diazaspiro[5.6]dodecan-11-yl)ethan-1-one (CAS 1422065-61-9)
- LG 100268 (CAS 153559-76-3)
- Benzamide, N-(2-aminoethoxy)- (CAS 222960-38-5)
- 2-[(2-Bromophenyl)sulfanyl]acetic acid (CAS 15939-85-2)
- Fudosteine Impurity 20 (CAS 1023971-10-9)
- Methyl 4-{[6-oxo-3-phenyl-4-(piperidin-1-yl)-1,6-dihydropyridazin-1-yl]methyl}benzoate (CAS 861208-95-9)
- (E)-N-(4-methoxybenzyl)-3-(3-((4-(trifluoromethyl)benzyl)oxy)phenyl)acrylamide (CAS 866151-71-5)
- N-(3-chloro-4-methylphenyl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 477333-97-4)
- Semaglutide impurity 50 (CAS 2773558-66-8)
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