N-((3,5-bis(trifluoromethyl)phenyl)sulfonyl)-N-phenylglycine CAS 339102-70-4
| CAS No. | 339102-70-4 |
| Molecular Formula | C16H11F6NO4S |
| Molecular Weight | 427.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-((3,5-bis(trifluoromethyl)phenyl)sulfonyl)-N-phenylglycine (CAS 339102-70-4) is a high-purity analytical reference standard with the molecular formula C16H11F6NO4S and a molecular weight of 427.32 g/mol.
The molecular framework of N-((3,5-bis(trifluoromethyl)phenyl)sulfonyl)-N-phenylglycine (C16H11F6NO4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-((3,5-bis(trifluoromethyl)phenyl)sulfonyl)-N-phenylglycine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11F6NO4S |
| Molecular Weight | 427.32 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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