2-[(4-Chlorophenyl)sulfanyl]-3-[3-(trifluoromethyl)phenyl]quinoline CAS 339103-22-9
| CAS No. | 339103-22-9 |
| Molecular Formula | C22H13ClF3NS |
| Molecular Weight | 415.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-[(4-Chlorophenyl)sulfanyl]-3-[3-(trifluoromethyl)phenyl]quinoline (CAS 339103-22-9), molecular formula C22H13ClF3NS and molecular weight 415.86 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-[(4-Chlorophenyl)sulfanyl]-3-[3-(trifluoromethyl)phenyl]quinoline (C22H13ClF3NS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 2-[(4-Chlorophenyl)sulfanyl]-3-[3-(trifluoromethyl)phenyl]quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H13ClF3NS |
| Molecular Weight | 415.86 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 2-[(2-Chlorophenyl)sulfanyl]-3-[3-(trifluoromethyl)phenyl]quinoline (CAS 339103-24-1)
- 3-(4-Chlorophenyl)-2-{[3-(trifluoromethyl)phenyl]sulfanyl}quinoline (CAS 339102-62-4)
- 5-((4-Chlorophenyl)thio)-N-(3-(trifluoromethyl)phenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 303151-35-1)
- Benzyl ((3-chlorophenyl)(phenylsulfonyl)methyl)carbamate (CAS 1017782-73-8)
- Ethyl 4-(4-chlorophenyl)-5-formyl-2-methyl-6-(pyrimidin-2-ylsulfanyl)-1,4-dihydropyridine-3-carboxylate (CAS 478261-85-7)
- N-(4-Chlorophenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775440-60-2)
- [(3Z)-1-[(4-Chlorophenyl)methyl]-5-nitro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino 3-methylbutanoate (CAS 303998-48-3)
- [(3Z)-1-[(4-Chlorophenyl)methyl]-5-nitro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino pentanoate (CAS 303998-37-0)
Recommended Standards
- Thiourea, N-(4-chlorophenyl)-N'-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]- (CAS 1013566-44-3)
- CP 316 819 (CAS 186392-43-8)
- Dacomitinib Impurity 2 (CAS CATO-C4X-20862)
- 13-((4-Chlorobenzyl)oxy)-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-dione (CAS 478029-46-8)
- Methyl 4-acetylpiperazine-2-carboxylate, 95% (CAS 1353945-27-3)
- 4-(4-Chlorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine (CAS 1707379-61-0)
- Ethyl 3,4,5-trimethoxybenzene-1-carboximidate hydrochloride (CAS 6383-98-8)
- 3-Bromo-3'-fluoro-4'-methylbenzhydrol (CAS 1443352-13-3)
- Telmisartan Impurity 45 (CAS 1098100-86-7)
- Ethyl 1-(4-aminophenyl)cyclopropanecarboxylate (CAS 1308814-99-4)
- 8-methyl-1,5-naphthyridin-4-ol (CAS 1099792-23-0)
- Methyl 4-(2-((2-hydroxy-2-methyl-4-(methylthio)butyl)amino)-2-oxoacetamido)benzoate (CAS 1396807-03-6)
- N-(4-amino-2-methylphenyl)isonicotinamide (CAS 33974-32-2)
- [D-Glu]3-Semaglutide (CAS CATO-C4X-2226253)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com