6-(Naphthalen-2-ylthio)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine CAS 339103-73-0
| CAS No. | 339103-73-0 |
| Molecular Formula | C16H9F3N4S |
| Molecular Weight | 346.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-(Naphthalen-2-ylthio)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 339103-73-0) is a high-purity analytical reference standard with the molecular formula C16H9F3N4S and a molecular weight of 346.33 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution, 6-(Naphthalen-2-ylthio)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 346.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H9F3N4S |
| Molecular Weight | 346.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Naphthalen Standards
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