2-(Naphthalen-1-yloxy)-N-(3-(trifluoromethyl)phenyl)acetamide CAS 333341-71-2
| CAS No. | 333341-71-2 |
| Molecular Formula | C19H14F3NO2 |
| Molecular Weight | 345.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(Naphthalen-1-yloxy)-N-(3-(trifluoromethyl)phenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(Naphthalen-1-yloxy)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 333341-71-2) is a high-purity analytical reference standard with the molecular formula C19H14F3NO2 and a molecular weight of 345.32 g/mol.
The molecular framework of 2-(Naphthalen-1-yloxy)-N-(3-(trifluoromethyl)phenyl)acetamide (C19H14F3NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14F3NO2 |
| Molecular Weight | 345.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Naphthalen Standards
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- N-(4-(naphthalen-1-yl)phenyl)naphthalen-1-amine (CAS 936916-07-3)
- 2-(Naphthalen-2-ylsulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole (CAS 62617-17-8)
- 6-(Naphthalen-2-ylthio)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 339103-73-0)
- Benzyl 3-(naphthalen-2-yl)piperazine-1-carboxylate (CAS 946384-25-4)
- 2-(4-Ethyl-5-((naphthalen-1-ylmethyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 578719-50-3)
- 1-(Naphthalen-2-yl)-3-((4-(trifluoromethyl)phenyl)amino)propan-1-one (CAS 883793-47-3)
Recommended Standards
- 1-(4-(Thiophen-2-yl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 955963-41-4)
- 2-Bromo-4,4'-di-tert-Butyl-1,1'-biphenyl (CAS 70728-89-1)
- (4Z)-3-Methyl-1-phenyl-4-({[3-(trifluoromethyl)phenyl]amino}methylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 320424-82-6)
- 3-Phenyl-4-[({[3-(trifluoromethyl)phenyl]methyl}amino)methylidene]-4,5-dihydro-1H-pyrazol-5-one (CAS 477850-66-1)
- Hexadecanoic-9,9-d2 Acid (CAS 272442-14-5)
- 1-(4-Chlorophenyl)cyclopentanamine Hydrochloride (CAS 1235439-77-6)
- 2,5-Dichloro-n'-hydroxybenzene-1-carboximidamide (CAS 872362-65-7)
- (2-Amino-3-(difluoromethyl)-5-methoxypyridin-4-yl)methanol (CAS 1805970-53-9)
- 5-fluoro-2-methyl-pyridin-3-amine (CAS 1256835-55-8)
- N,N-Diethyl-3-methoxyaniline (CAS 92-18-2)
- Ethyl 6-amino-5-cyano-2-[({5-cyano-[2,4'-bipyridine]-6-yl}sulfanyl)methyl]-4-(4-methoxyphenyl)-4H-pyran-3-carboxylate (CAS 313380-24-4)
- tert-Butyl (2,4-dihydroxyphenyl)carbamate (CAS 2228687-40-7)
- 5-Ethyl-3-(4-hydroxy-2-methylphenyl)-6-methyl-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1h)-one (CAS 777877-77-7)
- Pancreatic Polypeptide (31-36) Free Acid, human (CAS 192432-73-8)
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