3-(Pyridin-4-yl)-5-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole CAS 339104-45-9

Purity 97%+In StockPharmaceutical Standards
CAS No.339104-45-9
Molecular FormulaC14H8F3N3O
Molecular Weight291.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(Pyridin-4-yl)-5-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole CAS 339104-45-9 chemical structure

Description

The occurrence of 3-(Pyridin-4-yl)-5-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-(Pyridin-4-yl)-5-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole (CAS 339104-45-9) is a high-purity analytical reference standard with the molecular formula C14H8F3N3O and a molecular weight of 291.23 g/mol.

3-(Pyridin-4-yl)-5-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole (C14H8F3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H8F3N3O
Molecular Weight291.23 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms3

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