7-[3-(Trifluoromethyl)pyridin-2-yl]quinazolin-4-ol CAS 573675-81-7
| CAS No. | 573675-81-7 |
| Molecular Formula | C14H8F3N3O |
| Molecular Weight | 291.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 7-[3-(Trifluoromethyl)pyridin-2-yl]quinazolin-4-ol (CAS 573675-81-7), a certified reference material (molecular formula C14H8F3N3O, MW 291.23 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 7-[3-(Trifluoromethyl)pyridin-2-yl]quinazolin-4-ol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 291.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 7-[3-(Trifluoromethyl)pyridin-2-yl]quinazolin-4-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8F3N3O |
| Molecular Weight | 291.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 1-(6-Oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-2-yl)piperidine-4-carboxylic acid (CAS 1248546-34-0)
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- 4-{5-[2-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}pyridine (CAS 339104-49-3)
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- 2-{[2-methyl-4-(trifluoromethyl)-2h-pyrazolo[3,4-b]pyridin-6-yl]sulfanyl}acetic acid (CAS 1018046-75-7)
Recommended Standards
- Ethyl (Z)-3-[(3-methyl-1H-pyrazol-5-yl)amino]-2-(2,2,2-trifluoroacetyl)-2-propenoate (CAS 477709-41-4)
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- Ethyl 7-hydroxy-2-methyl-7-(trifluoromethyl)-4h,7h-pyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 923232-09-1)
- Ths-044 (CAS 62054-67-5)
- Ethyl 2-(5-bromopyridin-3-yl)benzo[d]oxazole-5-carboxylate (CAS 1706442-18-3)
- 3-[(2-Chlorophenyl)methyl]-4-phenyl-4,5-dihydro-1H-1,2,4-triazole-5-thione (CAS 497060-55-6)
- 4-(Aminomethyl)phenol hydrobromide (CAS 90430-14-1)
- 7-(1H-Indol-3-yl)heptan-1-amine (CAS 29852-47-9)
- 2-Hydroxy-4-methoxy-6-vinylbenzaldehyde (CAS 1403608-13-8)
- rel-2-((1R,2R)-2-(3-Methoxyphenyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1953178-11-4)
- 4-[2-(4-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]pyrimidin-2-amine (CAS 499795-93-6)
- 4-Chloro-3-(4-chlorophenyl)-3-fluoropropiophenone (CAS 898788-15-3)
- N-[1-(2-Naphthalenyl)ethyl]formamide (CAS 273384-77-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com