4-[4-(Diphenylmethyl)piperazin-1-yl]-N,N-dimethyl-6-(trifluoromethyl)pyrimidin-2-amine CAS 339105-18-9
| CAS No. | 339105-18-9 |
| Molecular Formula | C24H26F3N5 |
| Molecular Weight | 441.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[4-(Diphenylmethyl)piperazin-1-yl]-N,N-dimethyl-6-(trifluoromethyl)pyrimidin-2-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-[4-(Diphenylmethyl)piperazin-1-yl]-N,N-dimethyl-6-(trifluoromethyl)pyrimidin-2-amine (CAS 339105-18-9) is a high-purity analytical reference standard with the molecular formula C24H26F3N5 and a molecular weight of 441.49 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 4-[4-(Diphenylmethyl)piperazin-1-yl]-N,N-dimethyl-6-(trifluoromethyl)pyrimidin-2-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 441.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-[4-(Diphenylmethyl)piperazin-1-yl]-N,N-dimethyl-6-(trifluoromethyl)pyrimidin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H26F3N5 |
| Molecular Weight | 441.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Diphenylmethyl Standards
- 4-(Diphenylmethyl)-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)piperazine-1-carboxamide (CAS 866144-62-9)
- 2,6-Bis(diphenylmethyl)-4-methylbenzenamine (CAS 56138-96-6)
- 4-[4-(Diphenylmethyl)piperazin-1-yl]-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidine (CAS 339019-57-7)
- 4-[4-(Diphenylmethyl)piperazin-1-yl]-5-methoxy-2-phenylpyrimidine (CAS 477863-88-0)
- N2-[[5-(Diphenylmethyl)-2-furanyl]carbonyl]-L-Arginine hydrate (CAS 945254-73-9)
- Methyl 4-[4-(diphenylmethyl)piperazin-1-yl]-3-nitrobenzoate (CAS 478246-44-5)
- 2-{[4-(diphenylmethyl)piperazin-1-yl]methyl}-2H,3H,5H,6H-imidazo[1,2-c]quinazolin-5-one (CAS 477859-09-9)
- 5-[4-(Diphenylmethyl)piperazin-1-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbonitrile (CAS 318517-80-5)
Recommended Standards
- (4S)-3-[4-[2-(4-Fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone (CAS 953805-20-4)
- Isavuconazole-d4 (CAS 1346598-58-0)
- (R)-3-[4-[2-(4-Fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone (CAS 1478664-06-0)
- Ravuconazole Impurity 1 (CAS 1329499-27-5)
- 2-Nitroethane-1-sulfonyl chloride (CAS 97925-84-3)
- (1S,2S)-2-(dimethylamino)cyclohexan-1-ol (CAS 29783-01-5)
- 8-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-(trifluoromethyl)phenyl)-1-oxa-4,8-diazaspiro[4.5]Decane-4-carboxamide (CAS 338761-28-7)
- 4-Bromo-6-ethoxy-2-methylquinoline (CAS 1070879-46-7)
- Buspirone impurity 02 (CAS 87789-48-8)
- 1-([1,2,4]Triazolo[4,3-a]pyrazin-8-yl)-4-methylpyrrolidine-3-carboxylic acid (CAS 1394042-76-2)
- 2-(3-Aminopiperidin-1-yl)-6-ethylpyrimidin-4(3H)-one (CAS 1708428-19-6)
- n-Isopentyl-3-methylcyclohexan-1-amine (CAS 1019497-35-8)
- 2-(Cyclohexyloxy)-5-hydroxybenzenesulfonamide (CAS 1243479-27-7)
- Neuropeptide Y (2-36), amide, porcine (CAS 102961-52-4)
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