4-([1,1'-biphenyl]-4-yl)-N-(2-methoxyphenyl)thiazol-2-amine CAS 339204-45-4
| CAS No. | 339204-45-4 |
| Molecular Formula | C22H18N2OS |
| Molecular Weight | 358.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-([1,1'-biphenyl]-4-yl)-N-(2-methoxyphenyl)thiazol-2-amine is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-([1,1'-biphenyl]-4-yl)-N-(2-methoxyphenyl)thiazol-2-amine (CAS 339204-45-4), a certified reference material (molecular formula C22H18N2OS, MW 358.46 g/mol) for analytical method development and quality control.
The molecular framework of 4-([1,1'-biphenyl]-4-yl)-N-(2-methoxyphenyl)thiazol-2-amine (C22H18N2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-([1,1'-biphenyl]-4-yl)-N-(2-methoxyphenyl)thiazol-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H18N2OS |
| Molecular Weight | 358.46 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-{4-[(4-methylphenyl)methoxy]phenyl}-4-(thiophen-2-yl)pyrimidine (CAS 477862-32-1)
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- 4-allyl-5-[2-(4-methylphenyl)quinolin-4-yl]-4H-1,2,4-triazole-3-thiol (CAS 522598-07-8)
- 2-Propenoic acid, 2-methyl-, 2-[(1,1-dimethylethyl)amino]ethyl ester, polymer with butyl 2-propenoate, 2-hydroxyethyl 2-propenoate and methyl 2-methyl-2-propenoate (CAS 57635-61-7)
- Ethyl 3-amino-3-(3-(trifluoromethyl)phenyl)acrylate (CAS 68210-91-3)
- (Z)-3-(Benzylthio)acrylic acid (CAS 13831-02-2)
- 1-(Bromomethyl)-2-chloro-3-nitrobenzene (CAS 89642-16-0)
- 4-(3-Azabicyclo[3.2.2]nonan-3-yl)-1-(4-fluorophenyl)butan-1-one (CAS 15997-76-9)
- tert-Butyl 4-(1H-indol-5-yl)piperazine-1-carboxylate (CAS 478083-09-9)
- 2-Bromo-N-(2-methyl-4-nitrophenyl)propanamide (CAS 329208-83-5)
- 4-(4-methyl-1,3-thiazol-2-yl)butan-1-amine (CAS 1017422-97-7)
- Methyl 5,7-dichlorothieno[3,2-b]pyridine-3-carboxylate (CAS 2414358-16-8)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
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