3-((2-Chlorobenzyl)sulfonyl)-2-hydroxy-2-methyl-N-(3-(trifluoromethyl)phenyl)propanamide CAS 339275-65-9
| CAS No. | 339275-65-9 |
| Molecular Formula | C18H17ClF3NO4S |
| Molecular Weight | 435.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-((2-Chlorobenzyl)sulfonyl)-2-hydroxy-2-methyl-N-(3-(trifluoromethyl)phenyl)propanamide is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-((2-Chlorobenzyl)sulfonyl)-2-hydroxy-2-methyl-N-(3-(trifluoromethyl)phenyl)propanamide (CAS 339275-65-9), molecular formula C18H17ClF3NO4S and molecular weight 435.85 g/mol, is a CATO reference standard with documented purity and traceability.
3-((2-Chlorobenzyl)sulfonyl)-2-hydroxy-2-methyl-N-(3-(trifluoromethyl)phenyl)propanamide (C18H17ClF3NO4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-((2-Chlorobenzyl)sulfonyl)-2-hydroxy-2-methyl-N-(3-(trifluoromethyl)phenyl)propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17ClF3NO4S |
| Molecular Weight | 435.85 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorobenzyl Standards
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Recommended Standards
- 2-(((6-Chloropyridin-3-yl)methyl)thio)-6-(4-methoxyphenyl)-4-(trifluoromethyl)nicotinonitrile (CAS 664999-86-4)
- 3-[(2-Chlorophenyl)methanesulfonyl]-2-hydroxy-2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide (CAS 338956-22-2)
- 1-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}benzenesulfonyl)-4-methylpiperazine (CAS 344277-97-0)
- 3-[(4-Chlorophenyl)methanesulfonyl]-2-hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]propanamide (CAS 339275-64-8)
- 2-Chlorobenzoyl isothiocyanate (CAS 5067-90-3)
- Methyl 3-hydroxy-5-oxocyclohex-3-enecarboxylate (CAS 135365-38-7)
- 4-(1-Hydroxy-2-methylpropan-2-yl)thiomorpholine 1,1-dioxide (CAS 1566842-27-0)
- (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt (CAS 129622-68-0)
- (S)-2-Amino-2-(3-bromophenyl)ethan-1-ol hydrochloride (CAS 2095772-98-6)
- 1-(3,4-Difluorophenyl)-1,2,3,4-tetrahydroisoquinoline (CAS 1159998-06-7)
- 4-chloro-N-methyl-3-oxo-butanamide (CAS 1314919-68-0)
- 2,3-Diamino-5-nitrobenzoic acid (CAS 98279-87-9)
- Fomblin®; Y (CAS 69991-67-9)
- Calcitonin C-Terminal Flanking Peptide (human) XTFA (CAS 85916-47-8（free base）)
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