(E)-2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-4-(2-(thiophen-2-yl)vinyl)pyrimidine CAS 339278-44-3
| CAS No. | 339278-44-3 |
| Molecular Formula | C16H9ClF3N3S2 |
| Molecular Weight | 399.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-4-(2-(thiophen-2-yl)vinyl)pyrimidine (CAS 339278-44-3), molecular formula C16H9ClF3N3S2 and molecular weight 399.84 g/mol, is a CATO reference standard with documented purity and traceability.
(E)-2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-4-(2-(thiophen-2-yl)vinyl)pyrimidine (C16H9ClF3N3S2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-4-(2-(thiophen-2-yl)vinyl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H9ClF3N3S2 |
| Molecular Weight | 399.84 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
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Why CATO?
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