6-(((4-Chlorophenyl)thio)methyl)-N-(2-methoxybenzyl)-2-methylpyrimidin-4-amine CAS 339278-70-5
| CAS No. | 339278-70-5 |
| Molecular Formula | C20H20ClN3OS |
| Molecular Weight | 385.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-(((4-Chlorophenyl)thio)methyl)-N-(2-methoxybenzyl)-2-methylpyrimidin-4-amine is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-(((4-Chlorophenyl)thio)methyl)-N-(2-methoxybenzyl)-2-methylpyrimidin-4-amine (CAS 339278-70-5), molecular formula C20H20ClN3OS and molecular weight 385.91 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-(((4-Chlorophenyl)thio)methyl)-N-(2-methoxybenzyl)-2-methylpyrimidin-4-amine (C20H20ClN3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-(((4-Chlorophenyl)thio)methyl)-N-(2-methoxybenzyl)-2-methylpyrimidin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H20ClN3OS |
| Molecular Weight | 385.91 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 2-((4-Chlorophenyl)amino)-6-(cyclohexylthio)quinazolin-4(1H)-one (CAS 828261-89-8)
- 3-(2-Chlorophenyl)-4-((4-(diethylamino)benzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-27-2)
- 3-(3-Chlorophenyl)-4-((4-(diethylamino)benzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-14-0)
- 6-(((4-Chlorophenyl)thio)methyl)-N-(3-methoxybenzyl)-2-methylpyrimidin-4-amine (CAS 339278-87-4)
- N-(4-Chlorophenyl)-2-({3-cyano-5H,6H,7H,8H,9H,10H-cycloocta[b]pyridin-2-yl}sulfanyl)acetamide (CAS 444161-70-0)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2-isopropyl-6-methylphenyl)acetamide (CAS 329779-62-6)
- 2-[4-(3-Chlorophenyl)piperazin-1-yl]-N-(3,4-dihydro-2H-1-benzopyran-4-yl)acetamide (CAS 1147359-04-3)
- 4-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-N-(4-methyl-1,3-thiazol-2-yl)pyrimidin-2-amine (CAS 1823183-28-3)
Recommended Standards
- 3-Amino-N-(4-chlorophenyl)-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 625370-24-3)
- 3-Amino-N-(4-chlorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 387831-21-2)
- 7-Bromo-8-fluoro-6-iodo-1H-benzo[d][1,3]oxazine-2,4-dione (CAS 2678546-58-0)
- Azelastine-d3 (CAS 758637-88-6)
- 3-(1-Methyl-3-propylpyrrolidin-3-yl)phenyl acetate (CAS 1623-32-1)
- 5373-72-8 AR-1L3573 s-[2-({3-[(8-chloro-4-methylquinolin-2-yl)oxy]propyl}amino)ethyl] hydrogen sulfurothioate (CAS 5373-72-8)
- Ethyl 2-oxo-1,2-dihydro-1,5-naphthyridine-3-carboxylate (CAS 55234-61-2)
- (1-(Pyrazin-2-yl)azetidin-3-yl)methanol (CAS 1420969-03-4)
- Nalidixic Acid-D5 (CAS 1189467-36-4)
- tert-Butyl 2-(trimethylsilyl)piperidine-1-carboxylate (CAS 123387-54-2)
- 1-((4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)-2-(trityloxy)ethanone (CAS 681853-96-3)
- 2,4,4-Trimethylcyclohex-2-en-1-one (CAS 13395-71-6)
- 2-Cyclopentyl-9-(3-methoxyphenethyl)-1H-purin-6(9H)-one (CAS 834894-16-5)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
Why CATO?
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