6-(((4-Chlorophenyl)thio)methyl)-N-(3-methoxybenzyl)-2-methylpyrimidin-4-amine CAS 339278-87-4
| CAS No. | 339278-87-4 |
| Molecular Formula | C20H20ClN3OS |
| Molecular Weight | 385.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-(((4-Chlorophenyl)thio)methyl)-N-(3-methoxybenzyl)-2-methylpyrimidin-4-amine (C20H20ClN3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
6-(((4-Chlorophenyl)thio)methyl)-N-(3-methoxybenzyl)-2-methylpyrimidin-4-amine (CAS 339278-87-4), molecular formula C20H20ClN3OS and molecular weight 385.91 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-(((4-Chlorophenyl)thio)methyl)-N-(3-methoxybenzyl)-2-methylpyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H20ClN3OS |
| Molecular Weight | 385.91 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 2-((4-Chlorophenyl)amino)-6-(cyclohexylthio)quinazolin-4(1H)-one (CAS 828261-89-8)
- 3-(2-Chlorophenyl)-4-((4-(diethylamino)benzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-27-2)
- 3-(3-Chlorophenyl)-4-((4-(diethylamino)benzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-14-0)
- 6-(((4-Chlorophenyl)thio)methyl)-N-(2-methoxybenzyl)-2-methylpyrimidin-4-amine (CAS 339278-70-5)
- N-(4-Chlorophenyl)-2-({3-cyano-5H,6H,7H,8H,9H,10H-cycloocta[b]pyridin-2-yl}sulfanyl)acetamide (CAS 444161-70-0)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2-isopropyl-6-methylphenyl)acetamide (CAS 329779-62-6)
- 2-[4-(3-Chlorophenyl)piperazin-1-yl]-N-(3,4-dihydro-2H-1-benzopyran-4-yl)acetamide (CAS 1147359-04-3)
- 4-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-N-(4-methyl-1,3-thiazol-2-yl)pyrimidin-2-amine (CAS 1823183-28-3)
Recommended Standards
- 7-Bromo-8-fluoro-6-iodo-1H-benzo[d][1,3]oxazine-2,4-dione (CAS 2678546-58-0)
- 3-Amino-N-(4-chlorophenyl)-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 625370-24-3)
- Azelastine-d3 (CAS 758637-88-6)
- 3-Amino-N-(4-chlorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 387831-21-2)
- 73900-07-9 (~2~H_3_)Methyl trifluoromethanesulfonate DTXSID90583675 (CAS 73900-07-9)
- Methyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)acetate (CAS 885949-63-3)
- 2,5-Dibromo-3-(2-ethylhexyl)thiophene (CAS 444177-63-3)
- 3-(4-(tert-Butoxycarbonyl)phenyl)propanoic acid (CAS 86208-18-6)
- 3-Amino-1h-pyrazole-5-carboxylic acid hydrochloride (CAS 1032334-56-7)
- (11b,17b)-11-(1,3-Benzodioxol-5-yl)-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one (CAS 189035-07-2)
- 2-(Furan-2-yl)-5,6-dihydrofuro[2,3-d]pyrimidin-4-amine (CAS 61378-89-0)
- 1-(Pyrazin-2-yl)ethanesulfonyl chloride (CAS 1339345-11-7)
- 2-Methyl-5-nitroquinolin-4(3H)-one (CAS 1822947-46-5)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
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