(E)-2-(4-fluorophenoxy)-4-methoxy-N-((((2-methoxybenzyl)oxy)imino)methyl)nicotinamide CAS 341966-74-3
| CAS No. | 341966-74-3 |
| Molecular Formula | C22H20FN3O5 |
| Molecular Weight | 425.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-2-(4-fluorophenoxy)-4-methoxy-N-((((2-methoxybenzyl)oxy)imino)methyl)nicotinamide is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(E)-2-(4-fluorophenoxy)-4-methoxy-N-((((2-methoxybenzyl)oxy)imino)methyl)nicotinamide (CAS 341966-74-3), molecular formula C22H20FN3O5 and molecular weight 425.41 g/mol, is a CATO reference standard with documented purity and traceability.
(E)-2-(4-fluorophenoxy)-4-methoxy-N-((((2-methoxybenzyl)oxy)imino)methyl)nicotinamide (C22H20FN3O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H20FN3O5 |
| Molecular Weight | 425.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related E Standards
- N-(4-(2-((2-(4-Fluorophenoxy)ethyl)amino)-2-oxoethyl)thiazol-2-yl)-3-phenylacrylamide (CAS 1207061-71-9)
- 2-(2-Fluorophenoxy)-N-(2-((3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)oxy)ethyl)propanamide (CAS 1021112-42-4)
- (5-(4-Fluorophenoxy)-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 2-chlorobenzoate (CAS 318289-26-8)
- 3-{1-[2-(4-fluorophenoxy)acetyl]piperidin-4-yl}-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775313-81-9)
- (E)-6-(4-fluorophenoxy)nicotinaldehyde O-(4-bromobenzyl) oxime (CAS 866154-09-8)
- 2-(4-(4-Fluorophenoxy)-2-oxopyridin-1(2H)-yl)-4-methyl-N-(1-methyl-1H-pyrazol-3-yl)pentanamide (CAS 1262239-19-9)
- 3-(4-Fluorophenoxy)-6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene 1-oxide (CAS 477762-74-6)
- 3-{1-[2-(4-fluorophenoxy)acetyl]piperidin-4-yl}-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775357-55-5)
Recommended Standards
- ACT-709478, 98% (HPLC) (CAS 1838651-58-3)
- 2-(4-Acetamidophenyl)-N-(6-amino-3-(2-fluorobenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide (CAS 637335-11-6)
- 3,4-Dihydroxy-N-(4-methoxyphenyl)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonamide (CAS 1313738-89-4)
- Linezolid Impurity 26 (CAS 168828-89-5)
- 3-(5-Methoxy-2-(pyridin-2-ylmethoxy)phenyl)acrylic acid (CAS 924865-93-0)
- 2-Bromo-3-methyl-5-nitropyridine (CAS 23132-21-0)
- 2-(Difluoromethoxy)-6-ethoxyphenylpropanal (CAS 1804134-23-3)
- 1-(4-Chloropyridin-3-yl)ethanone (CAS 116922-73-7)
- 3,4,5-Tribenzyloxybenzyl Chloride (CAS 96277-83-7)
- Methyl 1-formyl-5,6,7,8-tetrahydroindolizine-2-carboxylate (CAS 1434051-76-9)
- Methyl 1-(2-ethoxy-2-oxoethyl)-6-(4-methoxyphenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011399-57-7)
- 4-Allyl-5-((4-chlorophenoxy)methyl)-4H-1,2,4-triazole-3-thiol (CAS 333767-06-9)
- (2E)-1-[4-(3-Methoxyphenyl)piperazin-1-yl]-2-phenyl-3-(thiophen-2-yl)prop-2-en-1-one (CAS 478078-53-4)
- Tau Peptide (295-309) trifluoroacetate salt (CAS 330456-46-7)
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