5-(tert-Butyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7-thiol CAS 34276-69-2
| CAS No. | 34276-69-2 |
| Molecular Formula | C9H12N4S |
| Molecular Weight | 208.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(tert-Butyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7-thiol is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-(tert-Butyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7-thiol (CAS 34276-69-2), a certified reference material (molecular formula C9H12N4S, MW 208.28 g/mol) for analytical method development and quality control.
The molecular framework of 5-(tert-Butyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7-thiol (C9H12N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(tert-Butyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12N4S |
| Molecular Weight | 208.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Recommended Standards
- 5-(tert-Butyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(6H)-thione (CAS 94341-98-7)
- 5-Ethoxy-1-methyl-1H-benzo[d]imidazole-2-thiol (CAS 302812-79-9)
- 5-(Pyrrolidine-1-carbonyl)pyridine-2-thiol (CAS 940271-60-3)
- 5-Ethyl-4-hydrazono-6-methyl-1,4-dihydrothieno[2,3-d]pyrimidine (CAS 439692-91-8)
- 4,4′-[(1E)-1,2-Diphenyl-1,2-ethenediyl]bis[benzaldehyde] (CAS 1421321-70-1)
- 2-Chloro-3-hydroxybenzonitrile (CAS 51786-11-9)
- Acetic acid,cobalt,(4S)-2-cyclopentyl-4-isopropyl-4,5-dihydrooxaz ole,palladium,(2,3,4-triphenylcyclobutyl)benzene (CAS 222400-03-5)
- 5-Chloro-n-(3-ethynylphenyl)thiophene-2-sulfonamide (CAS 1061371-88-7)
- 6-(3-Chlorophenyl)picolinimidamide hydrochloride (CAS 115193-76-5)
- Ilaprazole Impurity 137 (CAS CATO-C4X-1130137)
- 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1049606-32-7)
- 5-Bromo-3-fluoro-1H-pyrrolo[2,3-b]pyridine (CAS 1111637-68-3)
- 2-methylimidazo[1,2-a]pyridin-7-amine (CAS 1375110-97-6)
- semaglutide (CAS 782487-28-9)
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