7-Fluoro-4-hydroxyquinoline-3-carboxylic acid CAS 63463-20-7

Purity 97%+In StockPharmaceutical Standards
CAS No.63463-20-7
Molecular FormulaC10H6FNO3
Molecular Weight207.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Fluoro-4-hydroxyquinoline-3-carboxylic acid CAS 63463-20-7 chemical structure

Description

As a certified reference material (CRM), 7-Fluoro-4-hydroxyquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

7-Fluoro-4-hydroxyquinoline-3-carboxylic acid (CAS 63463-20-7) is a high-purity analytical reference standard with the molecular formula C10H6FNO3 and a molecular weight of 207.16 g/mol.

7-Fluoro-4-hydroxyquinoline-3-carboxylic acid (C10H6FNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC10H6FNO3
Molecular Weight207.16 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1975
Halogen ContentF-containing
Nitrogen Atoms1

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