Tryptophan Impurity 14 CAS 343-65-7
| CAS No. | 343-65-7 |
| Molecular Formula | C10H12N2O3 |
| Molecular Weight | 208.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tryptophan Impurity 14 (C10H12N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Tryptophan Impurity 14 (CAS 343-65-7), a pharmacopoeial impurity reference standard (molecular formula C10H12N2O3, MW 208.21 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12N2O3 |
| Molecular Weight | 208.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Tryptophan Standards
Recommended Standards
- Cefaclor Impurity 46 (CAS 134624-91-2&6453-64-1 (mixture))
- H-L-Phg-Gly-OH (CAS 134624-91-2)
- Atenolol Impurity 13 (CAS 72224-25-0)
- Cefaclor Degradation A Impurity(H-D-Phg-Gly-OH) (CAS 6453-64-1)
- Pantoprazole Impurity 5 (CAS 953787-60-5)
- Upadacitinib Impurity 68 (CAS CATO-C4X-240568)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
- 4-Bromopyrimidine Hydrochloride (CAS 1187931-22-1)
- 2-(Isoquinolin-1-yl)-2-methylpropanenitrile (CAS 81039-16-9)
- PBDES-Mix 10 (CAS CATO-LCEM100010-TO)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with ethenylbenzene and ethenyltriethoxysilane (CAS 25214-28-2)
- 1,1'-(1,3-Phenylene)bis(N,N-dimethylmethanamine) (CAS 19851-44-6)
- 3-(2-Methoxypyridin-3-yl)-1-methyl-1h-pyrazol-5-amine (CAS 1339624-34-8)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com