6-(Trifluoromethyl)isatin CAS 343-69-1
| CAS No. | 343-69-1 |
| Molecular Formula | C9H4F3NO2 |
| Molecular Weight | 215.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(Trifluoromethyl)isatin.
6-(Trifluoromethyl)isatin (CAS 343-69-1) is a high-purity analytical reference standard with the molecular formula C9H4F3NO2 and a molecular weight of 215.13 g/mol.
Structurally, 6-(Trifluoromethyl)isatin (C9H4F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 215.13 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-(Trifluoromethyl)isatin meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H4F3NO2 |
| Molecular Weight | 215.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 7-(Trifluoromethyl)pyrido[3,2-d]pyrimidin-4(3H)-one (CAS 1429870-20-1)
- 2-(Trifluoromethyl)-4H-benzo[d][1,3]oxazin-4-one (CAS 16062-71-8)
- 6-(Trifluoromethyl)benzo[d][1,2,3]triazin-4(3H)-one (CAS 1802389-77-0)
- 2-(Trifluoromethyl)pyrido[2,3-d]pyrimidin-4(3H)-one (CAS 338739-97-2)
- 4-(Trifluoromethyl)indoline-2,3-dione (CAS 386-73-2)
- 5-(Trifluoromethyl)phthalimide (CAS 1997-41-7)
- 6-(Trifluoromethyl)-1H-imidazo[4,5-b]pyridine-2-carbaldehyde (CAS 944904-88-5)
- 6-(Trifluoromethyl)benzo[d]oxazole-2-carbaldehyde (CAS 944898-85-5)
Recommended Standards
- 6-(Trifluoromethyl)pyrido[3,2-d]pyrimidin-4(3H)-one (CAS 946594-92-9)
- 7-(Trifluoromethyl)1H-indole-2,3-dione (CAS 391-12-8)
- 5,6,7-Trifluoro-1H-indole-2-carboxylic acid (CAS 247564-70-1)
- 5-(TRIFLUOROMETHYL)ISATIN (CAS 345-32-4)
- 5-Bromo-isoindole-1,3-dione (CAS 6941-75-9)
- 1-(4-Bromobutyl)-3-chlorobenzene (CAS 129254-79-1)
- N-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide (CAS 1105698-15-4)
- 3-Bromo-N-(4-methylpyridin-2-yl)benzamide (CAS 349405-36-3)
- 4-Cyclopropoxy-N-methyl-5-(methylthio)pyridin-2-amine (CAS 1243393-09-0)
- N-(7-Chloro-3-propionamidoquinoxalin-2-yl)hexanamide (CAS 61929-12-2)
- Bizelesin (CAS 129655-21-6)
- β-Oxo-2-benzofuranpropanenitrile (CAS 5149-69-9)
- tert-Butyl 4-((5-iodonaphthalen-1-yl)sulfonyl)-1,4-diazepane-1-carboxylate (CAS 1951444-75-9)
- D-[Arg]30-Semaglutide (CAS CATO-C4X-222653)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com