N-(5-chloroquinazolin-2-yl)-4-methylbenzamide CAS 343372-55-4

Description

The occurrence of N-(5-chloroquinazolin-2-yl)-4-methylbenzamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N-(5-chloroquinazolin-2-yl)-4-methylbenzamide (CAS 343372-55-4), a certified reference material (molecular formula C16H12ClN3O, MW 297.74 g/mol) for analytical method development and quality control.

Structurally, N-(5-chloroquinazolin-2-yl)-4-methylbenzamide (C16H12ClN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 297.74 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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