6-(4-Fluorophenoxy)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine CAS 343372-96-3
| CAS No. | 343372-96-3 |
| Molecular Formula | C12H6F4N4O |
| Molecular Weight | 298.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-(4-Fluorophenoxy)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 6-(4-Fluorophenoxy)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 343372-96-3), a certified reference material (molecular formula C12H6F4N4O, MW 298.20 g/mol) for analytical method development and quality control.
The molecular framework of 6-(4-Fluorophenoxy)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine (C12H6F4N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-(4-Fluorophenoxy)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H6F4N4O |
| Molecular Weight | 298.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluorophenoxy Standards
- 4-(5-((4-Fluorophenoxy)methyl)-1,2,4-oxadiazol-3-yl)benzaldehyde (CAS 1119450-77-9)
- 2-(4-fluorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 879906-49-7)
- (5-(4-Fluorophenoxy)-1-methyl-3-phenyl-1H-pyrazol-4-yl)methanol (CAS 318247-67-5)
- Ethyl 2-(2-((4-fluorophenoxy)methyl)morpholino)acetate (CAS 1706446-42-5)
- trans-3-(4-Fluorophenoxy)-4-hydroxy-1-Boc-pyrrolidine (CAS 1951440-06-4)
- 1-(2-(2-Fluorophenoxy)ethyl)-2-methyl-1H-indole-3-carbaldehyde (CAS 432003-58-2)
- 4-(4-Fluorophenoxy)-5-methoxy-2-(pyridin-2-yl)pyrimidine (CAS 338771-33-8)
- 2-(2-Fluorophenoxy)-N-(pyrazolo[1,5-a]pyridin-3-ylmethyl)acetamide (CAS 1396808-16-4)
Recommended Standards
- 4-{[(4-bromophenyl)sulfanyl]methyl}-3,5-dimethyl-1,2-oxazole (CAS 339099-95-5)
- 6-Bromo-2-piperazin-1-yl-1,3-benzothiazole (CAS 941869-85-8)
- tert-butyl N-[(5-bromo-1,3,4-thiadiazol-2-yl)methyl]carbamate (CAS 1454906-51-4)
- 1,8-Dinitroanthraquinone (CAS 129-39-5)
- Potassium ((cyclohexylamino)methyl)trifluoroborate (CAS 888711-52-2)
- 2-(2-Thienyl)azetidine (CAS 777886-76-7)
- tert-Butyl 3-bromo-2-propionyl-1H-indole-1-carboxylate (CAS 1707391-49-8)
- 6-Bromo-2,3-dimethoxyphenol (CAS 114605-75-3)
- Benzene Series MIX 7 (CAS CATO-MCEM500824-ME)
- 6-Hydroxy-2-(pyridin-2-yl)pyrimidine-4-carboxylic acid (CAS 84660-06-0)
- Benzyl N-({4-[(4-chlorophenyl)carbamoyl]phenyl}methyl)carbamate (CAS 477847-75-9)
- 2-(3-(4-Fluorophenyl)pyrazin-2-yl)thiazolidin-4-one (CAS 89442-19-3)
- 2-(Dipropylamino)-3-(2-methylprop-1-en-1-yl)quinolin-4(1H)-one (CAS 88960-27-4)
- Liraglutide Impurity 13 TFA Salt (CAS CATO-C4X-199213)
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