N-(2-((4-chlorobenzyl)thio)-2-methylpropyl)-4-methoxybenzenesulfonamide CAS 343372-99-6
| CAS No. | 343372-99-6 |
| Molecular Formula | C18H22ClNO3S2 |
| Molecular Weight | 399.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-(2-((4-chlorobenzyl)thio)-2-methylpropyl)-4-methoxybenzenesulfonamide (CAS 343372-99-6) is a high-purity analytical reference standard with the molecular formula C18H22ClNO3S2 and a molecular weight of 399.96 g/mol.
N-(2-((4-chlorobenzyl)thio)-2-methylpropyl)-4-methoxybenzenesulfonamide (C18H22ClNO3S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), N-(2-((4-chlorobenzyl)thio)-2-methylpropyl)-4-methoxybenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22ClNO3S2 |
| Molecular Weight | 399.96 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
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