N'-((5-(4-Chlorobenzyl)-6-oxo-2-thioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methylene)isonicotinohydrazide CAS 31349-14-1
| CAS No. | 31349-14-1 |
| Molecular Formula | C18H14ClN5O2S |
| Molecular Weight | 399.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N'-((5-(4-Chlorobenzyl)-6-oxo-2-thioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methylene)isonicotinohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N'-((5-(4-Chlorobenzyl)-6-oxo-2-thioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methylene)isonicotinohydrazide (CAS 31349-14-1), molecular formula C18H14ClN5O2S and molecular weight 399.85 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N'-((5-(4-Chlorobenzyl)-6-oxo-2-thioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methylene)isonicotinohydrazide (C18H14ClN5O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14ClN5O2S |
| Molecular Weight | 399.85 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(4-chlorobenzyl)-2,4-diphenylpyrimidine-5-carboxamide (CAS 321433-27-6)
- 2-((4-Chlorobenzyl)amino)-4-(4-cyclohexylphenyl)-4-oxobutanoic acid (CAS 1024023-22-0)
- N-(2-((4-chlorobenzyl)thio)-2-methylpropyl)-4-methoxybenzenesulfonamide (CAS 343372-99-6)
- 3,5-Bis((4-chlorobenzyl)thio)-1,2,4-thiadiazole (CAS 330551-83-2)
- 2-((4-Chlorobenzyl)amino)-N-(4-iodophenyl)acetamide (CAS 298215-15-3)
- 1-(4-Chlorobenzyl)-3-(morpholine-4-carbonyl)-6-(trifluoromethyl)pyridin-2(1H)-one (CAS 551921-70-1)
- N-(4-chlorobenzyl)-2-(4-(1-methyl-1H-indol-3-yl)butanoyl)hydrazine-1-carboxamide (CAS 866149-19-1)
- 1-Benzyl-2-((2-chlorobenzyl)thio)-5,6-dihydro-1H-imidazo[4,5-d]pyridazine-4,7-dione (CAS 3434-17-1)
Recommended Standards
- Methyl 2-amino-4-(2-chlorophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939894-13-0)
- Avanafil Impurity 78 (CAS 372117-76-5)
- 4-(4-Chlorobenzoyl)-1-(furan-2-ylmethyl)-3-hydroxy-5-(thiophen-2-yl)-1H-pyrrol-2(5H)-one (CAS 618074-50-3)
- (2Z)-3-[2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl]-2-(3-methoxyphenyl)prop-2-enenitrile (CAS 1164540-00-4)
- 5-(4-fluoro-2-methyl-phenyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one (CAS 2412839-53-1)
- Tert-butyl 4-(4-(1,3-dioxoisoindolin-2-yl)butyl)piperazine-1-carboxylate (CAS 745048-06-0)
- 3-(2-(4-Bromophenoxy)ethoxy)azetidine (CAS 1343824-68-9)
- Sodium 2-[(4-fluorophenyl)formamido]-3-(1H-indol-3-yl)propanoate (CAS 1396966-66-7)
- 1-(4-chlorophenyl)-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-one (CAS 173543-30-1)
- (5-Phenyl-1H-pyrazol-3-yl)methanol (CAS 179057-19-3)
- tert-Butyl 7’-fluoro-2’-oxo-2’,4’-dihydro-1’H-spiro[piperidine-4,3’-quinoline]-1-carboxylate (CAS 1393330-69-2)
- 3,5-Dimethyl-1H-isochromen-1-one (CAS 71568-82-6)
- 2-(Azidomethyl)-3,5-dimethylpyridin-4-ol (CAS 1211462-01-9)
- Liraglutide Impurity 6 TFA Salt (CAS CATO-C4X-19926)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com