N-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-iodobenzamide CAS 343373-53-5
| CAS No. | 343373-53-5 |
| Molecular Formula | C19H11ClF3IN2O2 |
| Molecular Weight | 518.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 518.66 g/mol gives N-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-iodobenzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-iodobenzamide (CAS 343373-53-5) is a high-purity analytical reference standard with the molecular formula C19H11ClF3IN2O2 and a molecular weight of 518.66 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, N-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-iodobenzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 518.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-iodobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H11ClF3IN2O2 |
| Molecular Weight | 518.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-[(1E)-{[(2,4-dichlorophenyl)methoxy]imino}methyl]benzamide (CAS 339026-61-8)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-(2,3,4,5,6-pentafluorophenyl)benzene-1-sulfonamide (CAS 338775-47-6)
- 3-{2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]pyridin-3-yl}-1-[3-(trifluoromethyl)phenyl]urea (CAS 338772-83-1)
- 7-Chloro-3-(3,4-dichlorophenyl)-1-((1-ethylpiperidin-3-yl)imino)-10-hydroxy-1,2,3,4-tetrahydroacridin-9(10H)-one (CAS 144128-42-7)
- 4-Chloro-N-[(N'-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carbonyl}hydrazinecarbonyl)methyl]benzamide (CAS 338397-24-3)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-[(1Z)-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}methyl]-1H-indole (CAS 338409-94-2)
- 4-(((4-(5-Chloro-2-(((1S,4r)-4-(((S)-1-methoxypropan-2-yl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (CAS 2247481-22-5)
- 6-(2-Chloro-4-(6-methylpyrazin-2-yl)phenyl)-8-ethyl-2-((2-(1-methylpiperidin-4-yl)ethyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 1432908-05-8)
Recommended Standards
- Alectinib Impurity 84 (CAS CATO-C4X-283684)
- Tiamulin - Impurity P (CAS 848129-54-4)
- Alectinib Impurity 80 (CAS CATO-C4X-283680)
- Odoroside A (CAS 12738-19-1)
- (3R,4S)-3-fluoropiperidin-4-ol hydrochloride (CAS 1523530-55-3)
- 2-((2-Methylpentyl)amino)propane-1,3-diol (CAS 1487013-77-3)
- Ethyl a-D-thiomannopyranoside (CAS 128946-17-8)
- 4-Phenyl-1-(m-tolyl)-1H-pyrazole-3-carboxylic acid (CAS 1245647-55-5)
- 3-methoxyfuran-2-carboxylic acid (CAS 88511-95-9)
- 36288-25-2 1-[2-(4-Methylphenyl)ethenyl]naphthalene DTXSID70733651 (CAS 36288-25-2)
- 3-Bromo-2-((tert-butoxycarbonyl)amino)-5-fluorobenzoic acid (CAS 2138125-26-3)
- 3-((4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl)-4-methoxybenzoic acid (CAS 1007515-16-3)
- EML 425 (CAS 1675821-32-5)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com