6-(2-Chloro-4-(6-methylpyrazin-2-yl)phenyl)-8-ethyl-2-((2-(1-methylpiperidin-4-yl)ethyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one CAS 1432908-05-8
| CAS No. | 1432908-05-8 |
| Molecular Formula | C28H32ClN7O |
| Molecular Weight | 518.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 518.05 g/mol gives 6-(2-Chloro-4-(6-methylpyrazin-2-yl)phenyl)-8-ethyl-2-((2-(1-methylpiperidin-4-yl)ethyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 6-(2-Chloro-4-(6-methylpyrazin-2-yl)phenyl)-8-ethyl-2-((2-(1-methylpiperidin-4-yl)ethyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 1432908-05-8), a certified reference material (molecular formula C28H32ClN7O, MW 518.05 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 6-(2-Chloro-4-(6-methylpyrazin-2-yl)phenyl)-8-ethyl-2-((2-(1-methylpiperidin-4-yl)ethyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 518.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H32ClN7O |
| Molecular Weight | 518.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
Related Chloro Standards
- 2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-(1’-hydroxy-2’-methoxymethyl)propanol (Mixture of Diastereomers) (CAS 184764-20-3)
- 2-((5-Chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzenesulfonamide (CAS 761438-38-4)
- 2-Chloro-4-methanesulfonyl-N-{4-[3-(trifluoromethyl)benzenesulfonyl]phenyl}benzamide (CAS 339105-03-2)
- (E)-4-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2-(2-(4-methoxybenzylidene)hydrazinyl)pyrido[2,3-b]pyrazin-3(4H)-one (CAS 338412-03-6)
- 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-{[(4-nitrophenyl)carbamothioyl]amino}-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 338399-31-8)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-3-[(1Z)-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}methyl]-1H-indole (CAS 338409-94-2)
- 4-Chloro-N-[(N'-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carbonyl}hydrazinecarbonyl)methyl]benzamide (CAS 338397-24-3)
- N-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-iodobenzamide (CAS 343373-53-5)
Recommended Standards
- 6,8-Dibromo-2-{4'-bromo-[1,1'-biphenyl]-4-yl}quinoline (CAS 861206-62-4)
- 3-Iodo-1H,1H,2H,2H,3H,4H,4H-perfluorodecan-1-ol (CAS 16083-68-4)
- 2-((3-(4-Chlorophenyl)-4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(naphthalen-1-yl)acetamide (CAS 586994-97-0)
- Pyronaridine (CAS 74847-35-1)
- 2-hydroxy-4-methyl-6-(methylthio)pyrimidine-5-carboxylic acid (CAS 929975-27-9)
- N-(2-bromo-4-methylphenyl)tetrahydro-2H-pyran-4-carboxamide (CAS 930547-90-3)
- 1-Chloro-n-ethyl-n-(2-methylbenzyl)methanesulfonamide (CAS 1343960-80-4)
- Propiverine Impurity 2 (CAS CATO-C4X-17402)
- 4-Amino-1,1,1-trifluoro-3-buten-2-one (CAS 184848-89-3)
- Ketoconazole Impurity 26 (CAS CATO-C4X-147226)
- Epalrestat impurity 48 (CAS CATO-C4X-223648)
- Rel-1-((1R,3r,5S)-bicyclo[3.1.0]hexan-3-yl)-6-(methylsulfonyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1365170-20-2)
- 6-Benzyl-3-phenyl-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one (CAS 892478-83-0)
- D-β-Asp9-Tirzepatide (CAS CATO-CPTD788932)
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