2-{[(4-methylphenyl)methyl]sulfanyl}-4-[(3-methylphenyl)sulfanyl]-5,6,7,8-tetrahydroquinazoline CAS 343374-10-7
| CAS No. | 343374-10-7 |
| Molecular Formula | C23H24N2S2 |
| Molecular Weight | 392.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-{[(4-methylphenyl)methyl]sulfanyl}-4-[(3-methylphenyl)sulfanyl]-5,6,7,8-tetrahydroquinazoline (CAS 343374-10-7) is a high-purity analytical reference standard with the molecular formula C23H24N2S2 and a molecular weight of 392.58 g/mol.
The molecular framework of 2-{[(4-methylphenyl)methyl]sulfanyl}-4-[(3-methylphenyl)sulfanyl]-5,6,7,8-tetrahydroquinazoline (C23H24N2S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H24N2S2 |
| Molecular Weight | 392.58 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related methylphenyl Standards
- 2-{[(4-methylphenyl)methyl]sulfanyl}-4-[(4-methylphenyl)sulfanyl]-5,6,7,8-tetrahydroquinazoline (CAS 478049-64-8)
- 4-[(1E)-3-(4-Methylphenyl)-3-oxoprop-1-en-1-yl]phenyl decanoate (CAS 331460-41-4)
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- 2-(4-Methylphenyl)-4-[(4-methylphenyl)sulfanyl]-5-(morpholin-4-yl)-2,3-dihydropyridazin-3-one (CAS 478067-00-4)
- N-(2-Methylphenyl)-2-[5-(morpholine-4-sulfonyl)-2-oxo-1,2-dihydropyridin-1-yl]acetamide (CAS 1251685-08-1)
- 3-(4-Methylphenyl)-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}prop-2-enamide (CAS 324562-68-7)
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Recommended Standards
- 2-((4-(Tert-butyl)benzyl)thio)-9-methyl-5H-thiochromeno[4,3-d]pyrimidine (CAS 478246-85-4)
- (5S,6E,8Z,10E,12R,14Z)-N-(3-Aminopropyl)-5,12-dihydroxyicosa-6,8,10,14-tetraenamide (CAS 89596-43-0)
- AUDA (CAS 479413-70-2)
- 2,4,5-Trimethyl-N-((1-(thiophen-3-ylmethyl)piperidin-4-yl)methyl)benzenesulfonamide (CAS 1235072-31-7)
- 3-Pyrrolidin-1-yladamantan-1-ol hydrochloride (CAS 1052406-65-1)
- (3-(1H-Pyrazol-1-yl)phenyl)methanamine hydrochloride (CAS 1245649-13-1)
- 8-(3-Fluorophenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine (CAS 1314787-78-4)
- trans,trans-4'-Propyl-4-(4-trifluoromethoxyphenyl)bicyclohexyl (CAS 133937-72-1)
- 2-Chloro-4-(piperidin-4-yloxy)benzonitrile (CAS 796600-10-7)
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-(o-tolyloxy)ethanone (CAS 304676-35-5)
- methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxylate (CAS 1040281-86-4)
- 3-(3-(Benzyloxy)propoxy)-2-hydroxybenzaldehyde (CAS 1093644-47-3)
- Anisatin (CAS 5230-87-5)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
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