1-{[5-(4-chlorophenyl)-1,2-oxazol-3-yl]methyl}-4-(2-fluorophenyl)piperazine CAS 343374-68-5
| CAS No. | 343374-68-5 |
| Molecular Formula | C20H19ClFN3O |
| Molecular Weight | 371.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-{[5-(4-chlorophenyl)-1,2-oxazol-3-yl]methyl}-4-(2-fluorophenyl)piperazine (C20H19ClFN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
1-{[5-(4-chlorophenyl)-1,2-oxazol-3-yl]methyl}-4-(2-fluorophenyl)piperazine (CAS 343374-68-5) is a high-purity analytical reference standard with the molecular formula C20H19ClFN3O and a molecular weight of 371.84 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H19ClFN3O |
| Molecular Weight | 371.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related chlorophenyl Standards
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Recommended Standards
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- Moxifloxacin Impurity 23 (CAS 154093-72-8)
- 7-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid hydrate (CAS 1923066-08-3)
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- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
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