(2Z)-3-(4-Chlorophenyl)-1-(2,4,5-trimethoxyphenyl)prop-2-en-1-one CAS 343374-76-5
| CAS No. | 343374-76-5 |
| Molecular Formula | C18H17ClO4 |
| Molecular Weight | 332.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2Z)-3-(4-Chlorophenyl)-1-(2,4,5-trimethoxyphenyl)prop-2-en-1-one.
(2Z)-3-(4-Chlorophenyl)-1-(2,4,5-trimethoxyphenyl)prop-2-en-1-one (CAS 343374-76-5) is a high-purity analytical reference standard with the molecular formula C18H17ClO4 and a molecular weight of 332.78 g/mol.
Structurally, (2Z)-3-(4-Chlorophenyl)-1-(2,4,5-trimethoxyphenyl)prop-2-en-1-one (C18H17ClO4) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 332.78 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H17ClO4 |
| Molecular Weight | 332.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Z Standards
- 1-(4-Chlorophenyl)-2-phenylquinazolin-4(1H)-one (CAS 1098-23-3)
- (2E)-1-(3-Chlorophenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one (CAS 1287193-96-7)
- (2-((2-Chlorophenyl)amino)thiazol-5-yl)(4-fluorophenyl)methanone (CAS 339022-57-0)
- (2-{[(4-Chlorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetic acid (CAS 929839-22-5)
- (2E)-1-(2-Chlorophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (CAS 282539-22-4)
- (2E)-1-(3-Chlorophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (CAS 849763-60-6)
- (3Z)-3-[(3-Chlorophenyl)imino]-1-phenyl-2,3-dihydro-1H-indol-2-one (CAS 303984-49-8)
- (3Z)-3-[(4-Chlorophenyl)imino]-1-phenyl-2,3-dihydro-1H-indol-2-one (CAS 303149-12-4)
Recommended Standards
- (4-Chloro-2-methylphenoxy)-[(2-methoxyphenyl)methylene]hydrazide Acetic Acid (CAS 356102-14-2)
- (5E)-5-(2-Chloro-6-fluorobenzylidene)-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one (CAS 404369-94-4)
- (5Z)-5-[(4-Chlorophenyl)methylidene]-3-(4-fluorophenyl)-2-sulfanylideneimidazolidin-4-one (CAS 338773-95-8)
- (R)-1-(11-Chloro-9-methyl-1,2,4a,5-tetrahydropyrazino[1',2':4,5][1,4]oxazino[3,2-g]quinazolin-3(4H)-yl)ethan-1-one (CAS 2793405-75-9)
- 5-(Methoxycarbonyl)-2-methylfuran-3-carboxylic acid (CAS 1359657-46-7)
- N,N-Dimethyl-5-(pyridin-3-ylmethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide (CAS 1775432-82-0)
- 1,2,3-Tribromo-1,1,2,3,3-pentamethyltrisilane (CAS 127725-93-3)
- 4-(3,4-Dimethoxyphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 2197053-18-0)
- 39901-94-5 Picolinoyl chloride hydrochloride, 2-(Chlorocarbonyl)pyridine hydrochloride pyridine-2-carbonyl chloride hydrochloride (CAS 39901-94-5)
- 2-Cyclopentylcyclohexan-1-ol (CAS 103984-62-9)
- [4-Amino-2-(trifluoromethyl)phenyl](4-methyl-1-piperazinyl)methanone (CAS 853297-04-8)
- 5-Bromo-2-fluoro-N-(pyridin-3-yl)benzamide (CAS 930674-31-0)
- N-(2-Bromophenyl)-4-fluorobenzamide (CAS 671-13-6)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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