3-(4-Chlorophenyl)-1-methyl-4-[3-(trifluoromethyl)benzoyl]pyrrolidine CAS 343374-74-3
| CAS No. | 343374-74-3 |
| Molecular Formula | C19H17ClF3NO |
| Molecular Weight | 367.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-Chlorophenyl)-1-methyl-4-[3-(trifluoromethyl)benzoyl]pyrrolidine is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(4-Chlorophenyl)-1-methyl-4-[3-(trifluoromethyl)benzoyl]pyrrolidine (CAS 343374-74-3), molecular formula C19H17ClF3NO and molecular weight 367.79 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C19H17ClF3NO, 3-(4-Chlorophenyl)-1-methyl-4-[3-(trifluoromethyl)benzoyl]pyrrolidine contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 367.79 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-Chlorophenyl)-1-methyl-4-[3-(trifluoromethyl)benzoyl]pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H17ClF3NO |
| Molecular Weight | 367.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- 3-(4-Chlorophenyl)-5-(3-fluoro-4-methoxyphenyl)-6-methylpyrazolo[1,5-a]pyrimidine (CAS 861207-17-2)
- 5-[(4-Chlorophenyl)methoxy]-2-(4-fluorophenyl)-7-methylimidazo[1,2-a]pyrimidine (CAS 866050-73-9)
- 4-[(4-Chlorophenyl)sulfanyl]-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 338418-08-9)
- 5-[(4-Chlorophenyl)sulfanyl]-3-phenyl-6-(trifluoromethyl)-1,2,4-triazine (CAS 383148-38-7)
- (2E)-3-(4-Chlorophenyl)-2-[5-(2-fluorobenzoyl)thiophen-2-yl]prop-2-enenitrile (CAS 338966-82-8)
- (2E)-3-(4-Chlorophenyl)-2-[5-(4-fluorobenzoyl)thiophen-2-yl]prop-2-enenitrile (CAS 338966-81-7)
- 6-(4-chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011397-66-2)
- 1-(4-Chlorophenyl)-5-[(E)-[(4-fluorophenyl)methylidene]amino]-6-imino-2-oxo-1,2,3,6-tetrahydropyrimidine-4-carbonitrile (CAS 1048915-26-9)
Recommended Standards
- 2-(5-(4-Chlorobenzyl)-4-oxo-4,5-dihydro-3H-pyridazino[4,5-b]indol-3-yl)acetic acid (CAS 903160-94-1)
- 5-(3-Chloro-4-fluorophenyl)-3-methyl-3-(5-pyrimidinylmethyl)indolin-2-one (CAS 1141080-83-2)
- 2-(5-(3-Chlorobenzyl)-4-oxo-4,5-dihydro-3H-pyridazino[4,5-b]indol-3-yl)acetic acid (CAS 903161-09-1)
- 5'-Chloro-2'-nitro-N-phenyl-malonanilic Acid-d5 Ethyl Ester (CAS 129973-74-6)
- 6-(Trifluoromethoxy)nicotinaldehyde (CAS 1361849-85-5)
- 1-((4-Nitrophenyl)sulfonyl)-1h-benzo[d]imidazole (CAS 1091-57-2)
- Suc-Ala-Trp-Pro-Phe-pNA (CAS 128822-32-2)
- 5-amino-1-methyl-2,3-dihydro-1H-indol-2-one hydrochloride (CAS 1790361-51-1)
- 2-(2-Chloro-6-fluorophenyl)cyclopropane-1-carboxylic acid (CAS 1157642-59-5)
- Dimethyl 3,4,5,6-tetrafluorophthalate (CAS 1024-59-5)
- 6-Methoxyisoquinoline-1-carbaldehyde (CAS 31181-33-6)
- 9-Chloro-5-isobutyl-2,3,5,6-tetrahydro-1H-azepino[4,5-b]indol-4-one (CAS 1380571-66-3)
- Safranal (CAS 116-26-7)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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