1-[4-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenoxy)-3-nitrophenyl]ethan-1-one CAS 343374-87-8
| CAS No. | 343374-87-8 |
| Molecular Formula | C21H14ClF3N2O4 |
| Molecular Weight | 450.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C21H14ClF3N2O4, 1-[4-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenoxy)-3-nitrophenyl]ethan-1-one contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 450.80 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-[4-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenoxy)-3-nitrophenyl]ethan-1-one (CAS 343374-87-8) is a high-purity analytical reference standard with the molecular formula C21H14ClF3N2O4 and a molecular weight of 450.80 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H14ClF3N2O4 |
| Molecular Weight | 450.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
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- 1-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1,4-diazepan-1-yl)-2-(1H-indol-3-yl)ethane-1,2-dione (CAS 497061-32-2)
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Recommended Standards
- Lauryl oleate (CAS 36078-10-1)
- N-[2-({[(dimethylcarbamothioyl)disulfanyl]methanethioyl}amino)ethyl][(dimethylcarbamothioyl)disulfanyl]carbothioamide (CAS 5836-23-7)
- D-erythro-Pentofuranosyl chloride, 2-deoxy-, bis(4-nitrobenzoate) (9CI) (CAS 51841-98-6)
- tert-Butyl 4-(4-bromophenyl)-4-(4-chlorophenyl)-piperidine-1-carboxylate (CAS 857532-23-1)
- 3-Methylisoxazole-4,5-diamine (CAS 524729-49-5)
- 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine (CAS 1355071-84-9)
- 5-((3,5-Dimethyl-1h-pyrazol-1-yl)methyl)furan-2-carbohydrazide (CAS 312309-47-0)
- Guaiazulene Impurity 4 (CAS CATO-C4X-22374)
- 5-Fluoro-2-pyridylzinc bromide solution (CAS 935433-87-7)
- (3-Bromobenzyl)hydrazine Dihydrochloride (CAS 1349715-79-2)
- 10-Methyl-9-(phenoxycarbonyl) acridinium (trifluoromethylsulfonate) (CAS 161006-14-0)
- Ceftazidime Impurity 50 (CAS 1924627-99-5)
- 2-((4-(Difluoromethoxy)-3-methoxybenzyl)thio)acetic acid (CAS 923149-01-3)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
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