6-Chloro-N2-(3,4-dichlorophenyl)-N4-(2-(1-methylpyrrolidin-2-yl)ethyl)quinazoline-2,4-diamine CAS 76004-86-9
| CAS No. | 76004-86-9 |
| Molecular Formula | C21H22Cl3N5 |
| Molecular Weight | 450.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Chloro-N2-(3,4-dichlorophenyl)-N4-(2-(1-methylpyrrolidin-2-yl)ethyl)quinazoline-2,4-diamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 6-Chloro-N2-(3,4-dichlorophenyl)-N4-(2-(1-methylpyrrolidin-2-yl)ethyl)quinazoline-2,4-diamine (CAS 76004-86-9), a certified reference material (molecular formula C21H22Cl3N5, MW 450.79 g/mol) for analytical method development and quality control.
Structurally, 6-Chloro-N2-(3,4-dichlorophenyl)-N4-(2-(1-methylpyrrolidin-2-yl)ethyl)quinazoline-2,4-diamine (C21H22Cl3N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 450.79 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C21H22Cl3N5 |
| Molecular Weight | 450.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
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- 8-Chloro-1-methylimidazo[1,5-a]pyrazine (CAS 1340877-38-4)
- 3-(2,5-Dimethylbenzyl)azetidin-3-ol (CAS 1509218-66-9)
- pyrazolo[1,5-a]pyridin-3-ol (CAS 51118-68-4)
- N-Boc-3-iodo-L-alanine Benzyl Ester (CAS 108957-20-6)
- C6 Urea Ceramide (CAS 486991-52-0)
- 2-methyltetrahydropyran-4-amine;hydrochloride (CAS 827046-87-7)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
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