2-{1-amino-2-[3-(trifluoromethyl)phenoxy]ethylidene}malononitrile CAS 343375-42-8
| CAS No. | 343375-42-8 |
| Molecular Formula | C12H8F3N3O |
| Molecular Weight | 267.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-{1-amino-2-[3-(trifluoromethyl)phenoxy]ethylidene}malononitrile (CAS 343375-42-8), a certified reference material (molecular formula C12H8F3N3O, MW 267.21 g/mol) for analytical method development and quality control.
2-{1-amino-2-[3-(trifluoromethyl)phenoxy]ethylidene}malononitrile (C12H8F3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2-{1-amino-2-[3-(trifluoromethyl)phenoxy]ethylidene}malononitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8F3N3O |
| Molecular Weight | 267.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related amino Standards
- Ethyl 5-amino-1-(2,4-difluorophenyl)-1H-pyrazole-3-carboxylate (CAS 1264039-33-9)
- Ethyl 5-amino-1-(2,5-difluorophenyl)-1H-pyrazole-4-carboxylate (CAS 138907-69-4)
- Ethyl 5-amino-1-(2,4-difluorophenyl)-1H-pyrazole-4-carboxylate (CAS 138907-72-9)
- Ethyl 5-amino-1-(3,5-difluorophenyl)-1H-pyrazole-4-carboxylate (CAS 1527946-98-0)
- 2-Amino-3-(3-fluoro-5-(trifluoromethoxy)phenyl)propanoic acid (CAS 1391002-18-8)
- 2-Amino-3-(2-fluoro-4-(trifluoromethoxy)phenyl)propanoic acid (CAS 1391008-15-3)
- 2-Amino-3-(4-fluoro-2-(trifluoromethoxy)phenyl)propanoic acid (CAS 1435806-18-0)
- 2-Amino-3-(5-fluoro-2-(trifluoromethoxy)phenyl)propanoic acid (CAS 1703955-84-3)
Recommended Standards
- 2-[(1H-1,2,4-Triazol-1-yl)methyl]-5-(trifluoromethyl)-1H-1,3-benzodiazole (CAS 321430-80-2)
- 3-(5-(Hydroxymethyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzonitrile (CAS 209919-64-2)
- 1-Methyl-5-phenoxy-3-(trifluoromethyl)-1H-pyrazole-4-carbonitrile (CAS 916766-95-5)
- 5-(Furan-2-yl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439111-88-3)
- N'-(4-methylbenzoyl)-2,5-bis(2,2,2-trifluoroethoxy)benzohydrazide (CAS 860788-23-4)
- 2-(2-Fluorophenoxy)propanoic acid (CAS 17088-71-0)
- 3-(4-Amino-6-(phenylamino)-1,3,5-triazin-2-yl)propanoic acid (CAS 91719-85-6)
- 1-(3-(Difluoromethyl)-2-fluorophenyl)ethan-1-amine (CAS 1391195-60-0)
- Elmycin B (CAS 128233-09-0)
- Glycyrrhizic Acid Impurity 4 (CAS 83896-44-0)
- Potassium dibenzyl phosphate (CAS 78543-37-0)
- 2,3,4,5-Tetrachlorotoluene (CAS 1006-32-2)
- 1-(Methoxymethyl)-3,3-dimethylcyclobutan-1-amine (CAS 2295052-67-2)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
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