5-(Furan-2-yl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine CAS 439111-88-3
| CAS No. | 439111-88-3 |
| Molecular Formula | C12H8F3N3O |
| Molecular Weight | 267.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(Furan-2-yl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439111-88-3) is a high-purity analytical reference standard with the molecular formula C12H8F3N3O and a molecular weight of 267.21 g/mol.
The molecular framework of 5-(Furan-2-yl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (C12H8F3N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8F3N3O |
| Molecular Weight | 267.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Furan Standards
- Furan-2-ylmethyl naphthalen-1-ylcarbamate (CAS 116373-26-3)
- 4-(Furan-2-yl)-6-(3-methoxyphenyl)pyrimidin-2-amine (CAS 1263215-40-2)
- 10-(Furan-2-ylmethyl)-2,3-dihydroimidazo[2,1-b]quinazolin-5(10H)-one (CAS 55536-49-7)
- 2-(Furan-2-yl)-7,8-dimethylquinoline-4-carboxylic acid (CAS 588695-31-2)
- Ethyl 2-[4-(furan-2-ylmethyl)-5-sulfanyl-4h-1,2,4-triazol-3-yl]acetate (CAS 863669-70-9)
- N-(Furan-2-ylmethyl)-3-methoxybenzenesulfonamide (CAS 670271-80-4)
- Ethyl 4-(furan-2-yl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 123629-45-8)
- 1-(3-(Furan-2-yl)-3-hydroxypropyl)-3-(thiophen-2-yl)urea (CAS 1421516-68-8)
Recommended Standards
- 3-(5-(Hydroxymethyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzonitrile (CAS 209919-64-2)
- 5-Fluoro-4-hydroxy-6,7-dimethoxyquinoline-3-carboxylic acid (CAS 2865832-67-1)
- 2-{1-amino-2-[3-(trifluoromethyl)phenoxy]ethylidene}malononitrile (CAS 343375-42-8)
- Lead, [carbonato(2-)-κO]- (CAS 790616-79-4)
- 4-(Azepan-1-yl)-3,5-dichloroaniline (CAS 1701830-25-2)
- 3-Iodo-4-isopropoxybenzoic acid (CAS 856167-47-0)
- 1-(3-Bromo-5-methoxyphenyl)ethanone (CAS 1073642-71-3)
- 2-Bromo-4,5-difluorobenzoyl chloride (CAS 103994-89-4)
- Polyacrylamide (CAS 9003-05-8)
- 2-Morpholinopyridin-3-amine dihydrochloride (CAS 1209994-09-1)
- Bzl-Gly-OH · HCl (CAS 7689-50-1)
- 3-Phenoxybenzonitrile (CAS 50789-45-2)
- 2,3-Dibromo-5-fluorobenzoyl chloride (CAS 1807056-40-1)
- Des-Ala28-Tirzepatide (CAS CATO-CPTD788945)
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