4-Acetamido-2-fluorobenzene-1-sulfonyl chloride CAS 344-70-7
| CAS No. | 344-70-7 |
| Molecular Formula | C8H7ClFNO3S |
| Molecular Weight | 251.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Acetamido-2-fluorobenzene-1-sulfonyl chloride (CAS 344-70-7), molecular formula C8H7ClFNO3S and molecular weight 251.66 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H7ClFNO3S, 4-Acetamido-2-fluorobenzene-1-sulfonyl chloride contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 251.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Acetamido-2-fluorobenzene-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7ClFNO3S |
| Molecular Weight | 251.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Acetamido Standards
- 3-Acetamido-5-fluorobenzenesulfonyl chloride (CAS 1393542-95-4)
- 3-acetamido-4-fluorobenzene-1-sulfonyl chloride (CAS 160233-26-1)
- 4-Acetamido-3-chlorobenzene-1-sulfonyl fluoride (CAS 25300-04-3)
- 4-Acetamido-3-fluorobenzenesulfonyl chloride (CAS 349-71-3)
- 3-Acetamido-5-methyladamantane-1-carboxylic acid (CAS 14670-96-3)
- 3-acetamido-3-(2-ethoxyphenyl)propanoic acid (CAS 1225494-93-8)
- 2-Acetamido-3-(4-hydroxy-2,6-dimethylphenyl)propanoic acid (CAS 1255098-61-3)
- 2-Acetamido-4-(2-methoxyphenyl)butanoic acid (CAS 1260662-76-7)
Recommended Standards
- 3-(2-Chloroacetamido)benzene-1-sulfonyl fluoride (CAS 658-97-9)
- 2-(4-Chloro-3-((trifluoromethyl)thio)phenyl)acetonitrile (CAS 2514625-02-4)
- 2-(1-Cyclohexenyl)butyric Acid (CAS 6627-68-5)
- Diethyl 2-(2-chloroacetamido)malonate (CAS 41394-71-2)
- N-(2-((3-(2-cyanophenoxy)-2-hydroxypropyl)amino)ethyl)morpholine-4-carboxamide (CAS 1638772-25-4)
- (2-Chloro-4-fluorobenzyl)(4-fluorophenyl)sulfane (CAS 1443303-46-5)
- Ammonium ((1R,2S,4S,7R)-3-bromo-1,7-dimethyl-2-oxobicyclo[2.2.1]heptan-7-yl)methanesulfonate (CAS 14575-84-9)
- 7-Amino-8-nitro-2-phenyl-4H-chromen-4-one (CAS 1548405-77-1)
- tert-Butyl (4-chlorocyclohexyl)carbamate (CAS 35426-68-7)
- N-(1,1-Dioxidotetrahydrothiophen-3-yl)-2-((8-isopropyl-4-methylquinolin-2-yl)thio)propanamide (CAS 1088185-14-1)
- 6-(4-Fluorophenyl)hexanoic acid (CAS 89326-72-7)
- 1-Methoxynaphthalen-2-amine (CAS 3178-03-8)
- 4-(4-(4-Bromophenyl)-5-((2-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 477333-28-1)
- RGD-targeted Proapoptotic Peptide trifluoroacetate salt (CAS 2243207-09-0)
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