Ethyl 2-Amino-4-(trifluoromethyl)thiazole-5-carboxylate CAS 344-72-9
| CAS No. | 344-72-9 |
| Molecular Formula | C7H7F3N2O2S |
| Molecular Weight | 240.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-Amino-4-(trifluoromethyl)thiazole-5-carboxylate.
CATO supplies Ethyl 2-Amino-4-(trifluoromethyl)thiazole-5-carboxylate (CAS 344-72-9), a certified reference material (molecular formula C7H7F3N2O2S, MW 240.20 g/mol) for analytical method development and quality control.
Ethyl 2-Amino-4-(trifluoromethyl)thiazole-5-carboxylate (C7H7F3N2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7F3N2O2S |
| Molecular Weight | 240.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- ethyl 2-amino-5-(trifluoromethyl)-1,3-thiazole-4-carboxylate (CAS 1820704-65-1)
- 2-Amino-4-(trifluoromethyl)benzene-1-sulfonamide (CAS 657-70-5)
- 2-Amino-5-(trifluoromethyl)benzenesulfonamide (CAS 201224-78-4)
- 4-Amino-2-(trifluoromethyl)-benzenesulfonamide (CAS 363-93-9)
- 2-Amino-3-(2-methoxy-5-nitrophenyl)propanoic acid (CAS 116366-23-5)
- Ethyl 4-amino-2-methoxy-5-nitrobenzoate (CAS 1219014-66-0)
- 2-Amino-3-(4-methoxy-3-nitrophenyl)propanoic acid (CAS 90899-87-9)
- 2-Amino-3-nitro-9H-fluoren-9-one (CAS 42135-32-0)
Recommended Standards
- Benzofuran-5-yl-difluoroacetic acid ethyl ester (CAS 943541-56-8)
- Ethyl 4,6-difluoro-3-methylbenzofuran-2-carboxylate (CAS 1994412-94-0)
- 6-Methyl-2-((trifluoromethyl)sulfonyl)pyridin-3-amine (CAS 2758088-90-1)
- m-Tolyl trifluoromethanesulfonate (CAS 32578-31-7)
- Ethyl trans-3-amino-1-methyl-cyclobutanecarboxylate (CAS 1408278-18-1)
- Ethyl 2-cyclopropylimidazo[2,1-b][1,3,4]thiadiazole-6-carboxylate (CAS 1211742-78-7)
- 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-4-(4-fluorophenyl)piperazine (CAS 478260-05-8)
- 4-[4-[2-(Cyclopropylmethoxy)-5-methylsulfonylbenzoyl]piperazin-1-yl]-3-fluorobenzonitrile (CAS 845609-54-3)
- Fmoc-β-Ala-L-Arg(NO2)- OH (CAS CATO-CPTD788975)
- N’-methyl(benzyloxy)carbohydrazide hydrochloride (CAS 880-21-7)
- 6-Chloro-2,4-difluoro-3-methylaniline (CAS 2300095-53-6)
- (1R)-2,2-dimethyl-1-(1,3-thiazol-2-yl)propan-1-amine (CAS 473733-23-2)
- 5-(2,6-Dichloro-4-methylphenyl)oxazole (CAS 2364585-01-1)
- Anorexigenic Peptide (CAS 69275-10-1)
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