3-((2,6-Dichlorobenzyl)oxy)-N-(2,4-difluorophenyl)thiophene-2-carboxamide CAS 344269-91-6
| CAS No. | 344269-91-6 |
| Molecular Formula | C18H11Cl2F2NO2S |
| Molecular Weight | 414.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-((2,6-Dichlorobenzyl)oxy)-N-(2,4-difluorophenyl)thiophene-2-carboxamide (CAS 344269-91-6) is a high-purity analytical reference standard with the molecular formula C18H11Cl2F2NO2S and a molecular weight of 414.25 g/mol.
3-((2,6-Dichlorobenzyl)oxy)-N-(2,4-difluorophenyl)thiophene-2-carboxamide (C18H11Cl2F2NO2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-((2,6-Dichlorobenzyl)oxy)-N-(2,4-difluorophenyl)thiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H11Cl2F2NO2S |
| Molecular Weight | 414.25 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dichlorobenzyl Standards
- 3-((2,4-Dichlorobenzyl)oxy)-N-(2,4-difluorophenyl)thiophene-2-carboxamide (CAS 339098-01-0)
- 3-((2,6-Dichlorobenzyl)oxy)-N-(3,4-difluorophenyl)thiophene-2-carboxamide (CAS 344269-97-2)
- 1-((2,4-Dichlorobenzyl)oxy)-6-nitro-2-phenyl-1H-benzo[d]imidazole (CAS 303148-93-8)
- 1-((2,6-Dichlorobenzyl)oxy)-6-nitro-2-phenyl-1H-benzo[d]imidazole (CAS 303148-91-6)
- 1-((3,4-Dichlorobenzyl)oxy)-6-nitro-2-phenyl-1H-benzo[d]imidazole (CAS 303148-95-0)
- Ethyl 3-((2,6-dichlorobenzyl)oxy)pyrido[1,2-a]indole-10-carboxylate (CAS 478067-94-6)
- 2-(2,4-Dichlorobenzyl)-6-phenyl-5-(piperidin-1-yl)pyridazin-3(2H)-one (CAS 478029-35-5)
- 2-(3,4-Dichlorobenzyl)-6-phenyl-5-(piperidin-1-yl)pyridazin-3(2H)-one (CAS 478029-39-9)
Recommended Standards
- 2-(5-Bromo-4-formyl-2-methoxyphenoxy)-N-(naphthalen-1-yl)acetamide (CAS 832674-61-0)
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- 2-(2-Bromo-4-formyl-6-methoxyphenoxy)-N-(naphthalen-1-yl)acetamide (CAS 692279-89-3)
- 1-(5-Bromo-1H-indol-3-yl)-2-(4-(pyrimidin-2-yl)piperazin-1-yl)ethane-1,2-dione (CAS 256417-42-2)
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- 2,3-Dichloroquinoxalin-6-amine (CAS 76089-01-5)
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