3-({[(2,4-dichlorophenyl)methyl]sulfanyl}methyl)-4-phenyl-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-4H-1,2,4-triazole CAS 344274-48-2
| CAS No. | 344274-48-2 |
| Molecular Formula | C24H18Cl2F3N3S2 |
| Molecular Weight | 540.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-({[(2,4-dichlorophenyl)methyl]sulfanyl}methyl)-4-phenyl-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-4H-1,2,4-triazole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-({[(2,4-dichlorophenyl)methyl]sulfanyl}methyl)-4-phenyl-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-4H-1,2,4-triazole (CAS 344274-48-2), a certified reference material (molecular formula C24H18Cl2F3N3S2, MW 540.45 g/mol) for analytical method development and quality control.
The molecular framework of 3-({[(2,4-dichlorophenyl)methyl]sulfanyl}methyl)-4-phenyl-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-4H-1,2,4-triazole (C24H18Cl2F3N3S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-({[(2,4-dichlorophenyl)methyl]sulfanyl}methyl)-4-phenyl-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-4H-1,2,4-triazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H18Cl2F3N3S2 |
| Molecular Weight | 540.45 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related dichlorophenyl Standards
- 3-{[(2,6-dichlorophenyl)methyl]sulfanyl}-5-({[(2,6-dichlorophenyl)methyl]sulfanyl}methyl)-4-phenyl-4H-1,2,4-triazole (CAS 344271-14-3)
- N-[({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]formamido}methanethioyl)amino]-2-(4-methylbenzenesulfonyl)acetamide (CAS 1022403-91-3)
- Ethyl 2-((5-(2,5-dichlorophenyl)furan-2-yl)methylene)-7-methyl-3-oxo-5-phenyl-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 324566-50-9)
- N-(3,5-Dichlorophenyl)-4-(2-{[(3,5-dichlorophenyl)carbamothioyl]amino}ethyl)piperazine-1-carbothioamide (CAS 866038-42-8)
- 2,6-Bis((5-(3,4-dichlorophenyl)furan-2-yl)methylene)cyclohexanone (CAS 301312-59-4)
- N-(2,4-Dichlorophenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 476484-97-6)
- N-(2,5-Dichlorophenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 477330-32-8)
- N-(2,6-Dichlorophenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 476485-58-2)
Recommended Standards
- 3-(((2,6-Dichlorobenzyl)thio)methyl)-4-phenyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazole (CAS 344271-54-1)
- Sitagliptin Impurity 2 (CAS 769195-20-2)
- 2,4-Di([1,1'-biphenyl]-4-yl)-6-(4-bromophenyl)-1,3,5-triazine (CAS 877456-11-6)
- 2-(3-((2R,3S)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxochroman-3-yl)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one (CAS 159194-98-6)
- n-(2-(Pyridin-4-yl)ethyl)benzo[d]thiazol-2(3h)-imine (CAS 1177291-47-2)
- 2-Chloro-1-{4-[(3,4-dimethoxyphenyl)methyl]piperazin-1-yl}ethan-1-one hydrochloride (CAS 1052550-61-4)
- 5-Amino-N-ethyl-1H-1,2,4-triazole-1-carboxamide (CAS 406205-21-8)
- 3,4,5-Triiodo-2,6-dimethylpyridine (CAS 98549-80-5)
- (2-Ethylphenyl)(pyridin-2-yl)methanone (CAS 1443307-17-2)
- Tioconazole EP Impurity B HCl (CAS 61675-62-5)
- Ethyl 5-phenylpyrazolo[1,5-a]pyridine-3-carboxylate (CAS 99446-40-9)
- 4-Hydroxy-2-methoxybenzo[d]oxazole (CAS 1804412-50-7)
- 4-Azetidinomethyl-3-chlorobenzophenone (CAS 898756-46-2)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
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