Tioconazole EP Impurity B HCl CAS 61675-62-5
| CAS No. | 61675-62-5 |
| Molecular Formula | C16H12Cl4N2OS |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tioconazole EP Impurity B HCl.
As a process- or degradation-related impurity, Tioconazole EP Impurity B HCl (CAS 61675-62-5, C16H12Cl4N2OSHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Tioconazole EP Impurity B HCl (C16H12Cl4N2OSHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 458.60 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12Cl4N2OS HCl |
| Molecular Weight | 458.60 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Tioconazole Standards
Recommended Standards
- Relugolix Impurity 213 (CAS CATO-C4X-2429213)
- Abemaciclib Impurity N4 (CAS 1231930-33-8)
- Posaconazole Impurity 105 (CAS CATO-C4X-1208105)
- 5-(Benzyloxy)-7-fluoro-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one (CAS 1883750-33-1)
- Sodium phosphate monobasic, AR (CAS 7558-80-7)
- 2-((3,5-Dichlorophenyl)sulfonyl)ethan-1-ol (CAS 101079-90-7)
- Febuxostat impurity 127 (CAS CATO-C4X-1162103)
- Levofloxacin Impurity 26 (CAS 157373-08-5)
- 3,6-Bis(5-bromo-2-pyridinyl)-2,5-dihydro-2,5-bis(2-octyldodecyl)pyrrolo[3,4-c]pyrrole-1,4-dione (CAS 1455028-34-8)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com