5-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(pyridin-2-yl)pyrimidine CAS 344278-06-4
| CAS No. | 344278-06-4 |
| Molecular Formula | C15H8ClF3N4 |
| Molecular Weight | 336.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(pyridin-2-yl)pyrimidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(pyridin-2-yl)pyrimidine (CAS 344278-06-4), a certified reference material (molecular formula C15H8ClF3N4, MW 336.70 g/mol) for analytical method development and quality control.
Structurally, 5-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(pyridin-2-yl)pyrimidine (C15H8ClF3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 336.70 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(pyridin-2-yl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H8ClF3N4 |
| Molecular Weight | 336.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(pyridin-3-yl)pyrimidine (CAS 1092345-48-6)
- 2-Chloro-N-[2-(2-fluorobenzoyl)-4-nitrophenyl]acetamide (CAS 76895-80-2)
- 5-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(pyridin-3-yl)pyrimidine (CAS 344278-34-8)
- 5-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(pyridin-4-yl)pyrimidine (CAS 344278-11-1)
- (2-Chloro-5-nitrophenyl)methyl 4-nitrobenzoate (CAS 331460-24-3)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfonyl)aniline (CAS 1221792-42-2)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-methyl-1H-imidazole-5-carboxamide (CAS 339012-13-4)
- Ethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)thiazole-4-carboxylate (CAS 257295-33-3)
Recommended Standards
- 3-(Chlorodifluoromethyl)-6-(2,4-difluorophenyl)-7h-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine (CAS 832739-42-1)
- 2-Amino-4-((5-chloro-2,6-difluoropyrimidin-4-yl)amino)benzenesulfonic acid (CAS 26592-28-9)
- 3-(4-(Trifluoromethyl)phenoxy)benzenesulfonylchloride (CAS 882014-01-9)
- 4-(2-(Trifluoromethyl)phenoxy)benzenesulfonylchloride (CAS 885950-91-4)
- Ethyl 6-methyl-4-(3-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 106720-50-7)
- tert-Butyl 4-(2-hydroxyethyl)benzoate (CAS 149325-40-6)
- (4-Chloro-6-(difluoromethyl)-5-(trifluoromethyl)pyridin-2-yl)methanol (CAS 1806985-54-5)
- N-(2-((3-Bromophenyl)(hydroxy)methyl)-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide (CAS 340696-19-7)
- Pcb No. 39 (CAS 38444-88-1)
- 2-Cyclopropyl-imidazo[1,2-a]pyrazin-3-amine (CAS 723286-63-3)
- 888-78-8 Benzamide, 4-amino-N-(2-methylphenyl)- 3-14-00-01062 (Beilstein Handbook Reference) 4-Amino-N-(2-methylphenyl)benzamide 4-Amino-N-(o-tolyl)benzamide Benzanilide, 4-amino-2'-methyl- BRN 2808360 (CAS 888-78-8)
- 1-Methyl-1h-pyrrole-2,5-dicarbaldehyde (CAS 37893-28-0)
- 2-Amino-5-bromobenzene-1,3-diol (CAS 2070867-62-6)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com