2-(2-Chloropyridin-3-yl)-5,6-dimethyl-1-[(2-methylphenyl)methyl]-1H-1,3-benzodiazole CAS 344279-65-8

Purity 97%+In StockPharmaceutical Standards
CAS No.344279-65-8
Molecular FormulaC22H20ClN3
Molecular Weight361.87 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2-Chloropyridin-3-yl)-5,6-dimethyl-1-[(2-methylphenyl)methyl]-1H-1,3-benzodiazole CAS 344279-65-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Chloropyridin-3-yl)-5,6-dimethyl-1-[(2-methylphenyl)methyl]-1H-1,3-benzodiazole.

2-(2-Chloropyridin-3-yl)-5,6-dimethyl-1-[(2-methylphenyl)methyl]-1H-1,3-benzodiazole (CAS 344279-65-8) is a high-purity analytical reference standard with the molecular formula C22H20ClN3 and a molecular weight of 361.87 g/mol.

2-(2-Chloropyridin-3-yl)-5,6-dimethyl-1-[(2-methylphenyl)methyl]-1H-1,3-benzodiazole (C22H20ClN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(2-Chloropyridin-3-yl)-5,6-dimethyl-1-[(2-methylphenyl)methyl]-1H-1,3-benzodiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC22H20ClN3
Molecular Weight361.87 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms3

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