(2-Fluoro-5-(trifluoromethoxy)phenyl)methanol CAS 344411-08-1
| CAS No. | 344411-08-1 |
| Molecular Formula | C8H6F4O2 |
| Molecular Weight | 210.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2-Fluoro-5-(trifluoromethoxy)phenyl)methanol (CAS 344411-08-1), molecular formula C8H6F4O2 and molecular weight 210.13 g/mol, is a CATO reference standard with documented purity and traceability.
(2-Fluoro-5-(trifluoromethoxy)phenyl)methanol (C8H6F4O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2-Fluoro-5-(trifluoromethoxy)phenyl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6F4O2 |
| Molecular Weight | 210.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 3-Fluoro-5-(2,2,2-trifluoroethoxy)phenol (CAS 1026796-69-9)
- (5-Fluoro-2-(trifluoromethoxy)phenyl)methanol (CAS 1092460-86-0)
- (2-Fluoro-4-(trifluoromethoxy)phenyl)methanol (CAS 1240257-07-1)
- (4-Fluoro-2-(trifluoromethoxy)phenyl)methanol (CAS 1242252-68-1)
- 4-Fluoro-5-(trifluoromethoxy)benzene-1,2-diamine (CAS 1804386-40-0)
- 4-Fluoro-3-(2,2,2-trifluoroethoxy)phenol (CAS 1881290-53-4)
- 2-Fluoro-6-methoxy-3-(trifluoromethyl)phenol (CAS 1881329-34-5)
- (3-Fluoro-4-(trifluoromethoxy)phenyl)methanol (CAS 886498-99-3)
Recommended Standards
- 3-(2,5-Difluorophenyl)furan-2,5-dione (CAS 1904621-55-1)
- (3-Fluoro-5-(trifluoromethoxy)phenyl)methanol (CAS 86256-47-5)
- (3R,4R,5S)-6,6-Difluoro-3,4,5-trihydroxycyclohex-1-enecarboxylic acid (CAS 701211-73-6)
- (4-Fluoro-3-(trifluoromethoxy)phenyl)methanol (CAS 86256-18-0)
- Methyl 5-chloro-1-[(4-chlorophenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 400087-49-2)
- 4,8-Bis[5-(2-ethylhexyl)-4-fluoro-2-thienyl]benzo[1,2-b:4,5-b′]dithiophene (CAS 1514905-24-8)
- 4-Iodo-1-butyne (CAS 43001-25-8)
- Bempedoic Acid Impurity 51 (CAS 2127387-65-7)
- 3-Bromo-5-ethoxy-4-[(4-fluorobenzyl)oxy]benzaldehyde (CAS 346611-55-0)
- 1-(5-Iodopyrimidin-4-yl)piperidin-4-one (CAS 1538235-07-2)
- 1-(2-Methylbenzyl)-1H-imidazole (CAS 87266-34-0)
- 7-Fluoro-1-isobutylindoline-2,3-dione (CAS 1190218-05-3)
- Esomeprazole Impurity 101 (CAS 84006-10-0)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com