2-Amino-6-(trifluoromethyl)pyridine CAS 34486-24-3
| CAS No. | 34486-24-3 |
| Molecular Formula | C6H5F3N2 |
| Molecular Weight | 162.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 162.11 g/mol gives 2-Amino-6-(trifluoromethyl)pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Amino-6-(trifluoromethyl)pyridine (CAS 34486-24-3) is a high-purity analytical reference standard with the molecular formula C6H5F3N2 and a molecular weight of 162.11 g/mol.
Based on its molecular formula C6H5F3N2, 2-Amino-6-(trifluoromethyl)pyridine contains a nitrile group, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 162.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5F3N2 |
| Molecular Weight | 162.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-Amino-4-(trifluoromethyl)pyridine (CAS 106447-97-6)
- 5-Amino-2-(trifluoromethyl)pyridine (CAS 106877-33-2)
- 3-Amino-4-(trifluoromethyl)pyridine (CAS 175204-80-5)
- 2-Amino-3-(trifluoromethyl)pyridine (CAS 183610-70-0)
- 2-Amino-5-(trifluoromethyl)pyridine (CAS 74784-70-6)
- 2-Amino-4-(carboxyamino)butanoic acid (CAS 134579-52-5)
- 3-Amino-5-cyanobenzoic acid (CAS 1000341-18-3)
- 3-Amino-2-cyanobenzoic acid (CAS 1369495-51-1)
Recommended Standards
- 3,4,5-Trifluoroanisole (CAS 203245-17-4)
- 2,5,5-Trifluoro-1-methyl-2,5-dihydro-1H-pyrrole-2-carbonitrile (CAS 363152-97-0)
- 3,4,5-Trifluorobenzyl Alcohol (CAS 220227-37-2)
- 2,4,6-Trifluoroanisole (CAS 219998-30-8)
- 1-Methyl-4-[methyl(pyridin-3-ylmethyl)sulfamoyl]-1h-pyrrole-2-carboxylic acid (CAS 937629-51-1)
- 4-(Difluoromethyl)-3-nitro-5-(trifluoromethyl)picolinonitrile (CAS 1807164-76-6)
- N'-[(1E)-(Thiophen-2-yl)methylidene]-2H-1,3-benzodioxole-5-carbohydrazide (CAS 1189062-66-5)
- Zinc chromate (CAS 13530-65-9)
- N-Boc-2-(2-morpholinyl)acetic Acid (CAS 766539-28-0)
- 4-(2-Hydroxy-3-methoxypropoxy)benzoic acid (CAS 3478-54-4)
- N-(2-(Cyclohex-1-en-1-yl)ethyl)-2-(1H-pyrrol-1-yl)thiazole-4-carboxamide (CAS 1207054-37-2)
- 5-Phenoxy-1-phenyl-1H-pyrazolo[3,4-b]pyrazine (CAS 87595-01-5)
- 2,3-Diaminoisonicotinic acid (CAS 1082930-45-7)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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