5-Phenyl[1,2,4]triazolo[4,3-c]quinazoline-3-thiol CAS 3455-46-7
| CAS No. | 3455-46-7 |
| Molecular Formula | C15H10N4S |
| Molecular Weight | 278.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Phenyl[1,2,4]triazolo[4,3-c]quinazoline-3-thiol (CAS 3455-46-7), molecular formula C15H10N4S and molecular weight 278.33 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Phenyl[1,2,4]triazolo[4,3-c]quinazoline-3-thiol (C15H10N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10N4S |
| Molecular Weight | 278.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Phenyl Standards
- [1,2,4]Triazolo[5,1-c][1,2,4]triazine, 7-bromo-4,6-dihydro-3-phenyl- (CAS 1416918-74-5)
- 5-Phenyl-[1,2,4]triazolo[4,3-a]quinoline-1-thiol (CAS 392237-33-1)
- 2-([1,2,4]Triazolo[3,4-b][1,3]benzothiazol-3-ylthio)propanoic acid (CAS 704875-01-4)
- N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)-2,2,2-trichloroacetamide (CAS 338419-09-3)
- 2-{[1,2,4]triazolo[4,3-a]quinoxalin-4-ylsulfanyl}pyrimidine (CAS 477853-41-1)
- 4-[(1-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}ethyl)carbamoyl]butanoic acid (CAS 1184188-37-1)
- 1-(5-Ethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidine-3-carboxylic acid (CAS 1707671-78-0)
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Recommended Standards
- 5-Methoxy-4-(4-methoxyphenoxy)-2-(methylsulfanyl)pyrimidine (CAS 338956-02-8)
- 6-(Benzo[d]thiazol-2-ylamino)-6-oxohexanoic acid (CAS 312614-93-0)
- 5-Ethylsulfadiazine (CAS 3271-01-0)
- 6-(Naphthalen-2-yl)imidazo[2,1-b]thiazole-5-carbaldehyde (CAS 562813-85-8)
- 2-{[(tert-butoxy)carbonyl]amino}-3-(1H-pyrrol-1-yl)propanoic acid (CAS 2044712-64-1)
- 6-amino-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-one (CAS 643087-29-0)
- 4-(Trifluoroacetamido)benzene-1-sulfonyl chloride (CAS 31143-71-2)
- 3-Chloro-6-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenoxy)pyridazine (CAS 338750-35-9)
- 4,5,6-Trimethyl-2,3-dihydrobenzofuran-7-carbaldehyde (CAS 89240-13-1)
- Chlormequat chloride D4 (1,1,2,2 D4) (CAS CATO-CCPD101951)
- N-Cyclopentyl-4-methylbenzamide (CAS 349403-36-7)
- tert-butyl N-(1-methyl-3-oxocyclobutyl)carbamate (CAS 1523617-99-3)
- (2-Phenylthiazol-4-yl)methanamine dihydrobromide (CAS 165736-03-8)
- Adrenal Peptide E, bovine (CAS 78355-50-7)
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