5-Phenyl-[1,2,4]triazolo[4,3-a]quinoline-1-thiol CAS 392237-33-1

Purity 97%+In StockPharmaceutical Standards
CAS No.392237-33-1
Molecular FormulaC16H11N3S
Molecular Weight277.34 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Phenyl-[1,2,4]triazolo[4,3-a]quinoline-1-thiol CAS 392237-33-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 277.34 g/mol gives 5-Phenyl-[1,2,4]triazolo[4,3-a]quinoline-1-thiol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Phenyl-[1,2,4]triazolo[4,3-a]quinoline-1-thiol (CAS 392237-33-1) is a high-purity analytical reference standard with the molecular formula C16H11N3S and a molecular weight of 277.34 g/mol.

5-Phenyl-[1,2,4]triazolo[4,3-a]quinoline-1-thiol (C16H11N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Phenyl-[1,2,4]triazolo[4,3-a]quinoline-1-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H11N3S
Molecular Weight277.34 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms3
Sulfur Atoms1

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