2-Amino-5-chloro-4-nitrobenzoic acid CAS 34649-02-0
| CAS No. | 34649-02-0 |
| Molecular Formula | C7H5ClN2O4 |
| Molecular Weight | 216.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 216.58 g/mol gives 2-Amino-5-chloro-4-nitrobenzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Amino-5-chloro-4-nitrobenzoic acid (CAS 34649-02-0) is a high-purity analytical reference standard with the molecular formula C7H5ClN2O4 and a molecular weight of 216.58 g/mol.
The molecular framework of 2-Amino-5-chloro-4-nitrobenzoic acid (C7H5ClN2O4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2O4 |
| Molecular Weight | 216.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-Amino-4-chloro-5-nitrobenzoic acid (CAS 100948-85-4)
- 2-Amino-4-chloro-6-nitrobenzoic acid (CAS 174456-26-9)
- 3-Amino-5-chloro-2-nitrobenzoic acid (CAS 193481-78-6)
- 2-Amino-3-chloro-5-nitrobenzoic acid (CAS 773109-32-3)
- 2-Amino-5-chloro-3-nitrobenzoic acid (CAS 6324-51-2)
- 2-Amino-6-chloro-3-nitrobenzoic acid (CAS 635317-45-2)
- 4-Amino-2-chloro-5-nitrobenzoic acid (CAS 82378-89-0)
- 4-Amino-3-chloro-5-nitrobenzoic acid (CAS 37902-01-5)
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