4-Amino-3-chloro-5-nitrobenzoic acid CAS 37902-01-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Amino-3-chloro-5-nitrobenzoic acid.

4-Amino-3-chloro-5-nitrobenzoic acid (CAS 37902-01-5), molecular formula C7H5ClN2O4 and molecular weight 216.58 g/mol, is a CATO reference standard with documented purity and traceability.

4-Amino-3-chloro-5-nitrobenzoic acid (C7H5ClN2O4) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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