Urapidil Impurity 78 CAS 34667-68-0
| CAS No. | 34667-68-0 |
| Molecular Formula | C19H27N5O3 |
| Molecular Weight | 373.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Urapidil Impurity 78 (C19H27N5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Urapidil Impurity 78 (CAS 34667-68-0, C19H27N5O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Urapidil Impurity 78 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H27N5O3 |
| Molecular Weight | 373.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 5 |
Related Urapidil Standards
- Urapidil Impurity 11 (CAS 91453-03-1)
- Urapidil Impurity 79 (CAS 88719-11-3)
- Urapidil Impurity 23 (CAS CATO-C4X-192423)
- Urapidil (CAS 34661-75-1)
- Urapidil Impurity 4 (CAS 34661-79-5)
- Urapidil Impurity 42 (CAS CATO-C4X-192442)
- Urapidil Impurity 58 (CAS CATO-C4X-192458)
- Urapidil Impurity 59 (CAS CATO-C4X-192459)
Recommended Standards
- Apixaban Impurity 125 (CAS CATO-C4X-1088125)
- Upadacitinib Impurity 3 (CAS CATO-C4X-24053)
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