1-Ethoxy-2,4-difluorobenzene CAS 348-20-9
| CAS No. | 348-20-9 |
| Molecular Formula | C8H8F2O |
| Molecular Weight | 158.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-Ethoxy-2,4-difluorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-Ethoxy-2,4-difluorobenzene (CAS 348-20-9) is a high-purity analytical reference standard with the molecular formula C8H8F2O and a molecular weight of 158.15 g/mol.
Structurally, 1-Ethoxy-2,4-difluorobenzene (C8H8F2O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 158.15 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8F2O |
| Molecular Weight | 158.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Ethoxy Standards
- 2-Ethoxy-1,3-difluorobenzene (CAS 946078-87-1)
- 2-Ethoxy-1,4-difluorobenzene (CAS 898538-70-0)
- 2-Ethoxy-4,5-dihydro-1H-imidazole-1-carboxylic acid (CAS 727968-25-4)
- 3-Ethoxy-4-methylpent-4-enoic acid (CAS 1384430-96-9)
- Ethyl 3-Ethoxy-2-butenoate (CAS 998-91-4)
- Ethyl 3-Ethoxy-2-methylpropyl-2-enoate (CAS 92145-32-9)
- trans-4-Ethoxy-1-ethylpyrrolidin-3-amine (CAS 1212212-82-2)
- (Z)-(1-Ethoxy-1-oxobut-2-en-2-yl)boronic acid (CAS 857284-86-7)
Recommended Standards
- 1,3-Difluoro-5-(methoxymethyl)benzene (CAS 228122-40-5)
- 2-(1,1-Difluoroethyl)pyridin-3-amine (CAS 2271475-31-9)
- 1,3-Difluoro-2-methoxy-5-methylbenzene (CAS 654-09-1)
- 2-(2,4-Difluorophenyl)ethanol (CAS 81228-02-6)
- 4-Bromo-1-(4-nitrobenzyl)-1h-pyrazole (CAS 957488-04-9)
- 5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-propoinic acid (CAS 658712-81-3)
- 2-(5-chloropyrazin-2-yl)propan-2-ol (CAS 1240596-83-1)
- 1-Ethylanthracene (CAS 66291-35-8)
- N-(2-bromo-4-methylphenyl)-3-chloro-6-methylbenzo[b]thiophene-2-carboxamide (CAS 332382-35-1)
- 3-Chloro-1-(4-(diethylamino)phenyl)isoquinoline-4-carbaldehyde (CAS 88456-04-6)
- N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-methyl-L-glutamine (CAS 910056-51-8)
- Ethyl 2,2-dimethyl-1,3-dioxane-5-carboxylate (CAS 82962-54-7)
- 2-Ethyl-2-(4-methyl-piperidin-1-ylmethyl)-hexanal (CAS 865074-67-5)
- Tirzepatide Impurity 51 (CAS CATO-C4X-324051)
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