1,2,7,8-Tetrachlorodibenzo-p-dioxin CAS 34816-53-0
| CAS No. | 34816-53-0 |
| Molecular Formula | C12H4Cl4O2 |
| Molecular Weight | 321.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,2,7,8-Tetrachlorodibenzo-p-dioxin.
1,2,7,8-Tetrachlorodibenzo-p-dioxin (CAS 34816-53-0), molecular formula C12H4Cl4O2 and molecular weight 321.97 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H4Cl4O2, 1,2,7,8-Tetrachlorodibenzo-p-dioxin contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 321.97 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H4Cl4O2 |
| Molecular Weight | 321.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
Related Tetrachlorodibenzo Standards
- 1,2,8,9-Tetrachlorodibenzo-p-Dioxin (CAS 116889-69-1)
- 1,3,7,9-Tetrachlorodibenzo-p-dioxin (CAS 116889-70-4)
- 1,2,6,8-Tetrachlorodibenzo-p-dioxin (CAS 67323-56-2)
- 1,2,8,9-Tetrachlorodibenzo-p-dioxin (CAS 62470-54-6)
- 1,3,6,8-Tetrachlorodibenzo-p-dioxin (CAS 33423-92-6)
- 1,3,7,9-Tetrachlorodibenzo-p-dioxin (CAS 62470-53-5)
- 1,4,7,8-Tetrachlorodibenzo-p-dioxin (CAS 40581-94-0)
- 1,3,7,8-Tetrachlorodibenzo-p-dioxin (CAS 50585-46-1)
Recommended Standards
- 2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine (CAS 1012785-51-1)
- 4-(5-Bromo-2-fluorophenyl)-2,6-dichloropyrimidine (CAS 1548193-78-7)
- 2,4-dichloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidine (CAS 928840-99-7)
- 4-(4-Bromo-2-fluorophenyl)-2,6-dichloropyrimidine (CAS 1545775-37-8)
- Methyl 3-amino-3-(2,5-difluorophenyl)propanoate (CAS 1270557-30-6)
- 4,4,4-Trifluoro-1-(pyridin-4-yl)butane-1,3-dione (CAS 399-06-4)
- 2,3-dichloro-5,6-dimethylbenzene-1,4-diamine (CAS 858012-57-4)
- 1-(5-Bromo-2-hydroxy-3-nitrophenyl)propan-1-one (CAS 90725-67-0)
- 3-(1-Ethylpiperidin-2-yl)-2-phenoxypyridine (CAS 1352500-54-9)
- tert-Butyl (2R)-2-(1H-imidazol-2-yl)pyrrolidine-1-carboxylate (CAS 1332326-40-5)
- 4-Bromo-2-iodo-6-methylbenzoic acid (CAS 1021344-68-2)
- 6-Bromo-2-methoxy-3-nitropyridine (CAS 58819-77-5)
- 5-((Trifluoromethyl)thio)pyrimidine-2,4(1H,3H)-dione (CAS 33216-83-0)
- Cycloaspeptide D (CAS 691363-62-9)
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