1,3,7,8-Tetrachlorodibenzo-p-dioxin CAS 50585-46-1
| CAS No. | 50585-46-1 |
| Molecular Formula | C12H4Cl4O2 |
| Molecular Weight | 321.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1,3,7,8-Tetrachlorodibenzo-p-dioxin (CAS 50585-46-1), a certified reference material (molecular formula C12H4Cl4O2, MW 321.97 g/mol) for analytical method development and quality control.
1,3,7,8-Tetrachlorodibenzo-p-dioxin (C12H4Cl4O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H4Cl4O2 |
| Molecular Weight | 321.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
Related Tetrachlorodibenzo Standards
- 1,2,8,9-Tetrachlorodibenzo-p-Dioxin (CAS 116889-69-1)
- 1,3,7,9-Tetrachlorodibenzo-p-dioxin (CAS 116889-70-4)
- 1,2,6,8-Tetrachlorodibenzo-p-dioxin (CAS 67323-56-2)
- 1,2,7,8-Tetrachlorodibenzo-p-dioxin (CAS 34816-53-0)
- 1,2,8,9-Tetrachlorodibenzo-p-dioxin (CAS 62470-54-6)
- 1,3,6,8-Tetrachlorodibenzo-p-dioxin (CAS 33423-92-6)
- 1,3,7,9-Tetrachlorodibenzo-p-dioxin (CAS 62470-53-5)
- 1,4,7,8-Tetrachlorodibenzo-p-dioxin (CAS 40581-94-0)
Recommended Standards
- 2,3,7,8-Tetrachloro-P-Dioxin (CAS 1746-01-6)
- 1,2,3,4-Tetrachlorodibenzo-p-dioxin (CAS 30746-58-8)
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