(5E)-5-(3-Fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one CAS 349-33-7
| CAS No. | 349-33-7 |
| Molecular Formula | C10H6FNOS2 |
| Molecular Weight | 239.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(5E)-5-(3-Fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (CAS 349-33-7) is a high-purity analytical reference standard with the molecular formula C10H6FNOS2 and a molecular weight of 239.29 g/mol.
Based on its molecular formula C10H6FNOS2, (5E)-5-(3-Fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 239.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6FNOS2 |
| Molecular Weight | 239.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related E Standards
- (E)-5-(2-Fluorobenzylidene)-2-mercaptothiazol-4(5H)-one (CAS 1784763-12-7)
- (Z)-5-(4-Fluorobenzylidene)-2-thioxothiazolidin-4-one (CAS 181765-53-7)
- (5E)-5-(4-Fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (CAS 402-93-7)
- (Z)-5-(2-Fluorobenzylidene)-2-thioxothiazolidin-4-one (CAS 917985-95-6)
- 3-(4-Fluorobenzylidene)-2-indolinone (CAS 3476-86-6)
- (Z)-3-(4-Fluorobenzylidene)isobenzofuran-1(3H)-one (CAS 105279-30-9)
- (Z)-5-(4-fluorobenzylidene)-3-methylthiazolidine-2,4-dione (CAS 366483-72-9)
- 4-((2-Fluorobenzylidene)amino)-5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 466644-97-3)
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